ID L7URR0_MYXSD Unreviewed; 614 AA.
AC L7URR0;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 61.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=MYSTI_08043 {ECO:0000313|EMBL:AGC49309.1};
OS Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Myxococcaceae; Myxococcus.
OX NCBI_TaxID=1278073 {ECO:0000313|EMBL:AGC49309.1, ECO:0000313|Proteomes:UP000011131};
RN [1] {ECO:0000313|EMBL:AGC49309.1, ECO:0000313|Proteomes:UP000011131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14675 / JCM 12634 / Mx s8
RC {ECO:0000313|Proteomes:UP000011131};
RX PubMed=23516218; DOI=10.1128/genomeA.00100-13;
RA Huntley S., Kneip S., Treuner-Lange A., Sogaard-Andersen L.;
RT "Complete genome sequence of Myxococcus stipitatus strain DSM 14675, a
RT fruiting myxobacterium.";
RL Genome Announc. 1:E0010013-E0010013(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP004025; AGC49309.1; -; Genomic_DNA.
DR AlphaFoldDB; L7URR0; -.
DR STRING; 1278073.MYSTI_08043; -.
DR KEGG; msd:MYSTI_08043; -.
DR PATRIC; fig|1278073.3.peg.8186; -.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_000445_114_44_7; -.
DR OrthoDB; 5377120at2; -.
DR Proteomes; UP000011131; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AGC49309.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000313|EMBL:AGC49309.1}.
FT DOMAIN 398..611
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 614 AA; 66179 MW; AB470E1C8316EFDB CRC64;
MEKHSSVSLR MPLPEEGQGS GVELLAENRR ARASAELASA RMRSLQSLTL ALSGALTSED
VARAVVVEAV RTLEAVAGGL YLMNVPGTSL ELVHSVRCPP AVEAAFTHVA LTARVPVAEA
VRTGAPLWLT DFATMAKHFP ETAAATRPTS GDMSVACLPL FTRARSVGCL IFVWGLAHDF
DEEERAFIDM LAQQATMALE RARLLAAERS QVERVGLLQH ATAMLATSLD LGHTLRGVAL
GLVPTLGDLC IIDVLGPDHE VRRHFHAATP ECSGLLAASR WHPPERPGTP ICALASGLTA
FHPSVDAFWI EGTSCGPEQL SLLRTLAPTS WMSVPLETPE GVLGALTLGH CLSGRHHTSE
DLALAVELAR RASAAVQNAH LFHQTQQALQ LRDEFLAIAS HELNTPLTAL KLQLSRLRRM
SADEDVQART SLAVQQVDRL GRLVRELLEV AHLSEGRLHL TPEPVDLVDV CRGVLTRFTE
ERERAGATIF LHATGAVPGR WDHSRVDGMV THLVSNALKY GLGRPVEVEV SCVPGDLARL
VVKDRGIGIP AEQLAHLFQR FGRAVPLRHY GGFGLGLWFS RQVVEAHGGH IHLESAPGLG
TTVTVEMPRT PASS
//
