ID L8EDM3_STRR1 Unreviewed; 493 AA.
AC L8EDM3;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Cytosine permease {ECO:0000313|EMBL:QST83756.1};
GN ORFNames=SRIM_029475 {ECO:0000313|EMBL:QST83756.1};
OS Streptomyces rimosus subsp. rimosus (strain ATCC 10970 / DSM 40260 / JCM
OS 4667 / NRRL 2234).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1265868 {ECO:0000313|EMBL:QST83756.1, ECO:0000313|Proteomes:UP000011074};
RN [1] {ECO:0000313|EMBL:QST83756.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 10970 {ECO:0000313|EMBL:QST83756.1};
RA Pethick F.E., MacFadyen A.C., Tang Z., Sangal V., Tze-Tze L., Chu J.,
RA Guo M., Kirby R., Hoskisson P.A., Herron P.R., Hunter I.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QST83756.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 10970 {ECO:0000313|EMBL:QST83756.1};
RA Algora L., Schniete J.K., MacFadyen A., Hoskisson P.A., Hunter I.S.,
RA Herron P.R.;
RL Submitted (JAN-2020) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:QST83756.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 10970 {ECO:0000313|EMBL:QST83756.1};
RA Algora-Gallardo L., Schniete J.K., Mark D.R., Hunter I.S., Herron P.R.;
RT "Bilateral symmetry of linear streptomycete chromosomes.";
RL bioRxiv 0:0-0(2021).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC {ECO:0000256|ARBA:ARBA00008974, ECO:0000256|PIRNR:PIRNR002744}.
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DR EMBL; CP048261; QST83756.1; -; Genomic_DNA.
DR RefSeq; WP_003987015.1; NZ_CP048261.1.
DR AlphaFoldDB; L8EDM3; -.
DR GeneID; 66858194; -.
DR Proteomes; UP000011074; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR InterPro; IPR001248; Pur-cyt_permease.
DR InterPro; IPR026030; Pur-cyt_permease_Fcy2/21/22.
DR PANTHER; PTHR31806; PURINE-CYTOSINE PERMEASE FCY2-RELATED; 1.
DR PANTHER; PTHR31806:SF1; PURINE-CYTOSINE PERMEASE FCY2-RELATED; 1.
DR Pfam; PF02133; Transp_cyt_pur; 1.
DR PIRSF; PIRSF002744; Pur-cyt_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002744};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR002744}.
SQ SEQUENCE 493 AA; 52194 MW; 212DE568E2D61FCB CRC64;
MGTTSTDTLS APETEGAVEQ RGIEPVPDHE RHGRVRELFP TWVAANISVL LLTMGASLVI
TNGLNFWQVL IVAAIASVVS FGMVGVLSVS GKWGGAPGAM LSRAAFGVRG NYFPGAILWV
ARFGWETINA VSGAYAVLTV LKLLFGIEAN NVLTVITLLL FVATTFLVSG MGRKALNICN
KYSTYLFSIF SVMVLVYLIA EMPWGKIFSQ SAGSTALMIA GIGTIAAGGI SWVPTGPDFA
RYLPHSASGK KIVGTTISGA ALVLVPMVLM GGIMAVSKPD LANQNTDPMS FLGEVLPTWL
AVPYLITALV GMLLINSLSM YSAGFTAQTM GVKLPRALAV SINAIISLVG GAFMMLVAKD
FIGQFITFLT LLAVSFSAWI GVYAVDMARR RNMAVRYDGD SLMDTTRTSR YWYAGGFCWQ
ALTAWGAALV VGLCLTKVTW FTGPLAETWP GKHGLGWAAT ILIAAVVFAV LPKPKETVPA
GAATLEKEPA PVG
//
