ID   L8ENL4_STRR1            Unreviewed;       471 AA.
AC   L8ENL4;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=Purine permease {ECO:0000313|EMBL:QST84318.1};
GN   ORFNames=SRIM_032830 {ECO:0000313|EMBL:QST84318.1};
OS   Streptomyces rimosus subsp. rimosus (strain ATCC 10970 / DSM 40260 / JCM
OS   4667 / NRRL 2234).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1265868 {ECO:0000313|EMBL:QST84318.1, ECO:0000313|Proteomes:UP000011074};
RN   [1] {ECO:0000313|EMBL:QST84318.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 10970 {ECO:0000313|EMBL:QST84318.1};
RA   Pethick F.E., MacFadyen A.C., Tang Z., Sangal V., Tze-Tze L., Chu J.,
RA   Guo M., Kirby R., Hoskisson P.A., Herron P.R., Hunter I.S.;
RL   Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:QST84318.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 10970 {ECO:0000313|EMBL:QST84318.1};
RA   Algora L., Schniete J.K., MacFadyen A., Hoskisson P.A., Hunter I.S.,
RA   Herron P.R.;
RL   Submitted (JAN-2020) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:QST84318.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 10970 {ECO:0000313|EMBL:QST84318.1};
RA   Algora-Gallardo L., Schniete J.K., Mark D.R., Hunter I.S., Herron P.R.;
RT   "Bilateral symmetry of linear streptomycete chromosomes.";
RL   bioRxiv 0:0-0(2021).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR   EMBL; CP048261; QST84318.1; -; Genomic_DNA.
DR   AlphaFoldDB; L8ENL4; -.
DR   Proteomes; UP000011074; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR   InterPro; IPR006043; NCS2.
DR   InterPro; IPR017588; UacT-like.
DR   InterPro; IPR006042; Xan_ur_permease.
DR   NCBIfam; TIGR00801; ncs2; 1.
DR   NCBIfam; NF037981; NCS2_1; 1.
DR   NCBIfam; TIGR03173; pbuX; 1.
DR   PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR   PANTHER; PTHR42810:SF4; URIC ACID TRANSPORTER UACT; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
SQ   SEQUENCE   471 AA;  48315 MW;  214C5CEAA63477FF CRC64;
     MAATPGRTAQ GDRKHPVDAT LPPFKMFTSG LQHVAAMYAG VVAPPMIVGP ACGLGPTETA
     FLVGAGLFTA GIATLLQTLG FWKIGAKLPF VNGVSFAGVT PMVAIGKAQS PGDALPVIFG
     AVIVAGVLGF LLAPYFSRLV RFFPPVVTGT VITLIGVSLL PVAFNWSQGG NATAHDYGSP
     VNIGMAALTF VIVLVLRRVL RGFLQQISIL LGLVAGTLIA IPVGITDFGA ITEAAPVGFP
     TPFHFGAPQF DAAAIVSMCI VMLVCMTEST ADMLALGKIV DRPADERTIE GGLRADTLGT
     AISPLFNGFA NSAFAQNIGL VAMTKVRSRF VVATGGLILV LLGLCPVAAS VISLVPLPVL
     GGAGIVLFGS VAASGIQTLA TAAMDKGENA LIVAASVGIG LIPIAAPRFY HDFPKDMLVV
     LDSGISTGCI VAIVLNLAFN HFGKRRGEPP LEVIPQQPER GAPDARPAGA H
//