ID L8ENN4_STRR1 Unreviewed; 300 AA.
AC L8ENN4;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE SubName: Full=NAD(P)-dependent oxidoreductase {ECO:0000313|EMBL:QST79279.1};
GN ORFNames=SRIM_003015 {ECO:0000313|EMBL:QST79279.1};
OS Streptomyces rimosus subsp. rimosus (strain ATCC 10970 / DSM 40260 / JCM
OS 4667 / NRRL 2234).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1265868 {ECO:0000313|EMBL:QST79279.1, ECO:0000313|Proteomes:UP000011074};
RN [1] {ECO:0000313|EMBL:QST79279.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 10970 {ECO:0000313|EMBL:QST79279.1};
RA Pethick F.E., MacFadyen A.C., Tang Z., Sangal V., Tze-Tze L., Chu J.,
RA Guo M., Kirby R., Hoskisson P.A., Herron P.R., Hunter I.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QST79279.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 10970 {ECO:0000313|EMBL:QST79279.1};
RA Algora L., Schniete J.K., MacFadyen A., Hoskisson P.A., Hunter I.S.,
RA Herron P.R.;
RL Submitted (JAN-2020) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:QST79279.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 10970 {ECO:0000313|EMBL:QST79279.1};
RA Algora-Gallardo L., Schniete J.K., Mark D.R., Hunter I.S., Herron P.R.;
RT "Bilateral symmetry of linear streptomycete chromosomes.";
RL bioRxiv 0:0-0(2021).
CC -!- SIMILARITY: Belongs to the HIBADH-related family.
CC {ECO:0000256|ARBA:ARBA00009080}.
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DR EMBL; CP048261; QST79279.1; -; Genomic_DNA.
DR RefSeq; WP_003983464.1; NZ_CP048261.1.
DR AlphaFoldDB; L8ENN4; -.
DR GeneID; 66852864; -.
DR Proteomes; UP000011074; Chromosome.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR048666; RedAm-like_C.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR Pfam; PF21761; RedAm-like_C; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
FT DOMAIN 4..157
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 163..287
FT /note="NADPH-dependent reductive aminase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21761"
SQ SEQUENCE 300 AA; 31955 MW; A5EB882CFBC0D62D CRC64;
MADVTVIGTG VIGSGVIRAC AAAGLEVAVW NRTERRARDV AAESPRIRVH PTAAGAIGAS
RTTLLCLLNY PVTHQVLEES GADLTGRLVV QHSSGVPESV GPLQDRVTGA GGRYMEAAIL
NYPDAIGTDA CFTVYGGAPE DFAELGPVTK AMSGHQVHLH AEPRYAKAYH VVASAFYYAF
VSGFLECAAI AEHIGVPLGA FADSVPLYDP GFENTVRVGL DLIERGDYHF EQAPLTTHID
VLENLTGAAE SAGIDASYLK ALRDRVRTAL DQGHRREHIA ILTEQFRARR GAAPRPMEGA
//
