ID L8FU82_PSED2 Unreviewed; 667 AA.
AC L8FU82;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Vacuolar protein sorting-associated protein 52 {ECO:0008006|Google:ProtNLM};
GN ORFNames=GMDG_06765 {ECO:0000313|EMBL:ELR04452.1};
OS Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) (Bat
OS white-nose syndrome fungus) (Geomyces destructans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=658429 {ECO:0000313|EMBL:ELR04452.1, ECO:0000313|Proteomes:UP000011064};
RN [1] {ECO:0000313|Proteomes:UP000011064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4855 / 20631-21 {ECO:0000313|Proteomes:UP000011064};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C.A., Blehert D.S., Lorch J.M., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Geomyces destructans 20631-21.";
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the VPS52 family.
CC {ECO:0000256|ARBA:ARBA00008180}.
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DR EMBL; GL573348; ELR04452.1; -; Genomic_DNA.
DR RefSeq; XP_012745207.1; XM_012889753.1.
DR AlphaFoldDB; L8FU82; -.
DR STRING; 658429.L8FU82; -.
DR VEuPathDB; FungiDB:GMDG_06765; -.
DR HOGENOM; CLU_010797_1_0_1; -.
DR InParanoid; L8FU82; -.
DR OrthoDB; 2723231at2759; -.
DR Proteomes; UP000011064; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR007258; Vps52.
DR InterPro; IPR048361; Vps52_C.
DR InterPro; IPR048319; Vps52_CC.
DR PANTHER; PTHR14190; SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52; 1.
DR PANTHER; PTHR14190:SF7; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG; 1.
DR Pfam; PF20655; Vps52_C; 1.
DR Pfam; PF04129; Vps52_CC; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000011064};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 161..327
FT /note="Vps52 coiled-coil"
FT /evidence="ECO:0000259|Pfam:PF04129"
FT DOMAIN 344..656
FT /note="Vps52 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF20655"
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..82
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 667 AA; 74746 MW; C3ABE26C40E3BD6F CRC64;
MWLDRLSGTS TPALRPNASS TPQSRSYSPV PRKTSRLLPQ TGPQRPNFSP RSSSLSAVSN
DSTTSLLGNS RKPTDSSSSN LRNITLTYSD PIQVLDKLLN IDLGNLPVAD KDEIWDNDEL
LGNVDFTGLA LHEFVQEDDV NTVQVSEAPA AARYEIDKAR FEDLHQSIRA CNDILNSVEL
NLTSFQNDLG DVSAEIETLR ARSTTLSSRI ENRKVVELGL TPVVEDITVS QTIVKTISEG
DIDESWIVAL NVVGKWSKAL NAKAIEAHNI KSITDLKPLR DQLVNIAIER IRDFLVAQIK
ALRSPNINAQ VVQQRHFIRY KDLFSFLWNH HQTLAEEIGQ AYMNTMRWYY LNHFTRYERA
LSKVKIHAID KHDVLGNDDS PRKSTLLTTS KATGPPHDAF SLGRRNDILT TSNQSALPSH
LAEDTATHYL EFPFRNFNLA LIDNVCAEYS FLTTFFSPSL SFHTIARYFN YIFSPTFELG
HTLTKSLVSE TFDSFGLLLC VRLNQKFNFK LQRHKIPVGD SYINGTNMLL WPRFQVIMDL
HCESVRKLTA NLPTAPPTSK AELAKQSAAP SSMAQRFGQL IQGILELSKE TGDDEPVSTS
LARLRSALEA FLARVAKTIE GERKRERFLE NSFSLILTII GDAQGKLATE QISQIQAMMT
TASQDTK
//
