ID L8FV64_PSED2 Unreviewed; 488 AA.
AC L8FV64;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Thioredoxin domain-containing protein {ECO:0000259|PROSITE:PS51352};
GN ORFNames=GMDG_06742 {ECO:0000313|EMBL:ELR04373.1};
OS Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) (Bat
OS white-nose syndrome fungus) (Geomyces destructans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=658429 {ECO:0000313|EMBL:ELR04373.1, ECO:0000313|Proteomes:UP000011064};
RN [1] {ECO:0000313|Proteomes:UP000011064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4855 / 20631-21 {ECO:0000313|Proteomes:UP000011064};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C.A., Blehert D.S., Lorch J.M., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Geomyces destructans 20631-21.";
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL573347; ELR04373.1; -; Genomic_DNA.
DR RefSeq; XP_012745184.1; XM_012889730.1.
DR AlphaFoldDB; L8FV64; -.
DR STRING; 658429.L8FV64; -.
DR VEuPathDB; FungiDB:GMDG_06742; -.
DR HOGENOM; CLU_030577_0_0_1; -.
DR InParanoid; L8FV64; -.
DR OrthoDB; 52245at2759; -.
DR Proteomes; UP000011064; Unassembled WGS sequence.
DR CDD; cd03002; PDI_a_MPD1_like; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 2.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR017937; Thioredoxin_CS.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR45815; PROTEIN DISULFIDE-ISOMERASE A6; 1.
DR PANTHER; PTHR45815:SF3; PROTEIN DISULFIDE-ISOMERASE A6; 1.
DR Pfam; PF00085; Thioredoxin; 1.
DR PRINTS; PR00421; THIOREDOXIN.
DR SUPFAM; SSF52833; Thioredoxin-like; 2.
DR PROSITE; PS00194; THIOREDOXIN_1; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011064};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..488
FT /note="Thioredoxin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003989244"
FT DOMAIN 14..143
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
FT REGION 242..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 256..287
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 291..313
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 488 AA; 52169 MW; 3DE9F0A51CAE56A9 CRC64;
MVYTGALAAA ATVLLLASPA TAAGLYPKSS MVLQVDAKNY DRLIAKSNYT SIVEFYAPWC
GHCKNLQPAY ENAAKKLAGL AKVAAVNCDE DINKQFCGSM GVQGFPTLKI VKPGKKFGKP
IVEDYQGARE AKPIVEAVSA KIANHVSKVT DKELDAFMAE NVDTHKAILF TEKGSTSSLL
KAIAIDFLGG IKVSQIRSKE PRAVEMFGIE KFPTIVLLPA GNGASATTYD GELKKDDIVK
FLSSVHPPNP DPAPAKGKAS KEKKAEKKSE KKTDKKAAKK AEEEFEEASS SQMESEASAS
ATAETSEEAS EPTESPSPEA EKPVVLTPPI PVITSEAELA DACLTPKSGT CVLAFTSAKG
GDVSVQSIES LAEVAFKYQN SKHAIFPFYA VAEEVTGMPG LKTALGLTND VDVVAINAKR
GWMRKYSGDV YTHEAIEMWI DSIRMGEGDK QILPGILIGK TPEQVAQTKT IQVEATEPTE
TVSVKDEL
//
