ID L8FYK8_PSED2 Unreviewed; 428 AA.
AC L8FYK8;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Sialidase domain-containing protein {ECO:0000259|Pfam:PF13088};
GN ORFNames=GMDG_07022 {ECO:0000313|EMBL:ELR04796.1};
OS Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) (Bat
OS white-nose syndrome fungus) (Geomyces destructans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=658429 {ECO:0000313|EMBL:ELR04796.1, ECO:0000313|Proteomes:UP000011064};
RN [1] {ECO:0000313|Proteomes:UP000011064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4855 / 20631-21 {ECO:0000313|Proteomes:UP000011064};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C.A., Blehert D.S., Lorch J.M., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Geomyces destructans 20631-21.";
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL573363; ELR04796.1; -; Genomic_DNA.
DR RefSeq; XP_012745471.1; XM_012890017.1.
DR AlphaFoldDB; L8FYK8; -.
DR STRING; 658429.L8FYK8; -.
DR VEuPathDB; FungiDB:GMDG_07022; -.
DR HOGENOM; CLU_024620_1_1_1; -.
DR InParanoid; L8FYK8; -.
DR OrthoDB; 5482010at2759; -.
DR Proteomes; UP000011064; Unassembled WGS sequence.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13088; BNR_2; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011064};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..428
FT /note="Sialidase domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003989865"
FT DOMAIN 72..399
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13088"
SQ SEQUENCE 428 AA; 44754 MW; 1278E7C644904AE5 CRC64;
MLYASQSMLR YAISVISLCA LSSVLTPVQA APAPSTVHSR ELFSQQVLAT NGVGPAPYYR
IVALANLGNG VILAAYDGRP DGSDSPAPNS IIQRRSTDGG DTWGAPTYIA QGQPGSTGVQ
KYGFSDPSYV VDQDTGKIFN FHVFSKNVGF GSSVIGNDDA NLNVISSEVS VSTDGGVSWS
TDPQNQPSLP PAASSLITKV VKPLGHTVNG VANVGGVIDK FAASGEGIQL RYGAHAGRLI
QQFVGRVIQP SGNIIYQAYS VYSDDGGSTW HMGSPVGVGM DENKVVELSN GNVMLNSRPS
DGSGYRKVAI STDGGITYST PKSETQLPDP ANNGAIIRMY PDAAEGSANA KILLFTNANS
QTSRVQGKAR YSCNDGTTWS AGRVFQAGAM SYSTITALGG DTFGIFYEGQ GNTLIFAKVD
KAWLGVSC
//
