ID L8FZR8_PSED2 Unreviewed; 741 AA.
AC L8FZR8;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Transcription initiation factor TFIID subunit 5 {ECO:0000256|ARBA:ARBA00044130};
GN ORFNames=GMDG_01930 {ECO:0000313|EMBL:ELR05968.1};
OS Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) (Bat
OS white-nose syndrome fungus) (Geomyces destructans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=658429 {ECO:0000313|EMBL:ELR05968.1, ECO:0000313|Proteomes:UP000011064};
RN [1] {ECO:0000313|Proteomes:UP000011064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4855 / 20631-21 {ECO:0000313|Proteomes:UP000011064};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C.A., Blehert D.S., Lorch J.M., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Geomyces destructans 20631-21.";
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the WD repeat TAF5 family.
CC {ECO:0000256|ARBA:ARBA00009435}.
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DR EMBL; GL573193; ELR05968.1; -; Genomic_DNA.
DR RefSeq; XP_012740332.1; XM_012884878.1.
DR AlphaFoldDB; L8FZR8; -.
DR STRING; 658429.L8FZR8; -.
DR VEuPathDB; FungiDB:GMDG_01930; -.
DR HOGENOM; CLU_005884_0_2_1; -.
DR InParanoid; L8FZR8; -.
DR OrthoDB; 3138699at2759; -.
DR Proteomes; UP000011064; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR CDD; cd08044; TAF5_NTD2; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.25.40.500; TFIID subunit TAF5, NTD2 domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR006594; LisH.
DR InterPro; IPR007582; TFIID_NTD2.
DR InterPro; IPR037264; TFIID_NTD2_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19879:SF1; CANNONBALL-RELATED; 1.
DR PANTHER; PTHR19879; TRANSCRIPTION INITIATION FACTOR TFIID; 1.
DR Pfam; PF08513; LisH; 1.
DR Pfam; PF04494; TFIID_NTD2; 1.
DR Pfam; PF00400; WD40; 6.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00667; LisH; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF160897; Taf5 N-terminal domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50896; LISH; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000011064};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 82..212
FT /note="TFIID subunit TAF5 NTD2"
FT /evidence="ECO:0000259|Pfam:PF04494"
FT REPEAT 369..410
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 426..475
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 483..514
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 525..568
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 569..610
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 619..646
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 656..702
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 658..695
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 741 AA; 81206 MW; FA17281E854208B3 CRC64;
MSNHPSQTPG AGPPSGSMGM PTGQQQPPIP PPVQNMSQQN LNQIVIEYLM KKGYLRTEQV
LRQESAQVDK DGRPIFGRDE YGNEKYIRGF ELLSSWIDSN LDIYKFELNR LLWPVYVYSF
IELITDMFTE DAKKFLQQFR PRFEKNHADE LRIFETISLK SHVLENPVAK LYRENKYRIP
LNAHVNFNLI SFLEGQGKKG GSIVLNILQT YCQVVETSRG PIDQYSFEAI VNRARGVGVD
EVVDLQEGIP GGFTGVSNQD LANNDAPVRL GPLQTETELT DDVRAELLEA DTKNPPAPGQ
QSLVEAYEQK IKREESADAI LRTEIPLPPS KARDVVMEVQ KMKESRDRFK IEGRTGGVGP
AVSVCMFTFH NTLDTITCME FSDDNNLVAI GTEESYIRVW NMHGEALKST LSGGPSDAPP
SNSRRLIGHS ASVYSVSFAP SIAGPEGPSS AVPSTGSNLL LSCSSDKSIR LWSLDAWTCL
VVYKGHEGPV WNVRWGPFGH YFVSCGWDKT VRVWTQDHIS YVRMLVGHDS SVNQIAWHPN
NAYVFSASDQ VDKTVRMWSV VTGQCVRIFN GHTDFISTLE CSPSGKILAS ADGGGSIILW
DLAKGTQIKR CRGHGKGGIW SLSFSAESTV LTSGGADGTV RIWDVEVPSD PYKGSDGDLI
GSSNQPDATR ITANGTAGAQ SAAPSGGSSG AMTGVTTGKK KGKDMVITPD QISAFPTKRS
PVYKVKFTRM NLAVAGGCYL P
//
