ID   L8G0P2_PSED2            Unreviewed;       831 AA.
AC   L8G0P2;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   24-JAN-2024, entry version 39.
DE   RecName: Full=AP-1 complex subunit gamma {ECO:0000256|PIRNR:PIRNR037094};
GN   ORFNames=GMDG_07438 {ECO:0000313|EMBL:ELR05516.1};
OS   Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) (Bat
OS   white-nose syndrome fungus) (Geomyces destructans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=658429 {ECO:0000313|EMBL:ELR05516.1, ECO:0000313|Proteomes:UP000011064};
RN   [1] {ECO:0000313|Proteomes:UP000011064}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4855 / 20631-21 {ECO:0000313|Proteomes:UP000011064};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C.A., Blehert D.S., Lorch J.M., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA   Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA   Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA   Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The genome sequence of Geomyces destructans 20631-21.";
RL   Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC       {ECO:0000256|PIRNR:PIRNR037094}.
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DR   EMBL; GL573392; ELR05516.1; -; Genomic_DNA.
DR   RefSeq; XP_012745889.1; XM_012890435.1.
DR   AlphaFoldDB; L8G0P2; -.
DR   STRING; 658429.L8G0P2; -.
DR   VEuPathDB; FungiDB:GMDG_07438; -.
DR   HOGENOM; CLU_003824_0_0_1; -.
DR   InParanoid; L8G0P2; -.
DR   OrthoDB; 25313at2759; -.
DR   Proteomes; UP000011064; Unassembled WGS sequence.
DR   GO; GO:0030121; C:AP-1 adaptor complex; IEA:InterPro.
DR   GO; GO:0005829; C:cytosol; IEA:GOC.
DR   GO; GO:0016482; P:cytosolic transport; IEA:UniProt.
DR   GO; GO:0016197; P:endosomal transport; IEA:UniProt.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.60.40.1230; -; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR017107; AP1_complex_gsu.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR   InterPro; IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
DR   InterPro; IPR013041; Clathrin_app_Ig-like_sf.
DR   InterPro; IPR008153; GAE_dom.
DR   PANTHER; PTHR22780; ADAPTIN, ALPHA/GAMMA/EPSILON; 1.
DR   PANTHER; PTHR22780:SF5; AP-1 COMPLEX SUBUNIT GAMMA; 1.
DR   Pfam; PF01602; Adaptin_N; 1.
DR   Pfam; PF02883; Alpha_adaptinC2; 1.
DR   PIRSF; PIRSF037094; AP1_complex_gamma; 1.
DR   SMART; SM00809; Alpha_adaptinC2; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF49348; Clathrin adaptor appendage domain; 1.
DR   PROSITE; PS50180; GAE; 1.
PE   3: Inferred from homology;
KW   Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329,
KW   ECO:0000256|PIRNR:PIRNR037094};
KW   Golgi apparatus {ECO:0000256|PIRNR:PIRNR037094};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037094};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW   ECO:0000256|PIRNR:PIRNR037094};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037094}.
FT   DOMAIN          719..831
FT                   /note="GAE"
FT                   /evidence="ECO:0000259|PROSITE:PS50180"
FT   REGION          595..628
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        595..609
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   831 AA;  90873 MW;  982F651812D41DDE CRC64;
     MSSLKQFIRN VRASKTIADE RAVVQKESAA IRASFREESG DHNVRRNNVA KLLYLFTLGE
     RTHFGQIECL KLLASPRFAD KRLGYLGTML LLDENQEVLT LVTNSLKNDL NHSNQYVVGL
     ALCTLGNIAS VEMSRDLFPE IETLISTANP YIRRKAALCA MRICRKVPDL QENFVDKAAN
     LLSDRNHGVL LCGLTLVTSL CEADEAEGGE EGIVEKFRPL SGQLVRTLKG LASSGYSPEH
     DVTGITDPFL QVKILQLLRV LGHGDVQTSE HINDILAQVA TNTDSTKNVG NSILYEAVLT
     ILDIEADSGL RVLGVNILGK FLANRDNNIR YVALNTLIKV VAIEPNAVQR HRNTILECLR
     DPDISIRRRA LDLSFTLINE SNVRVLIREL LAFLEVADNE FKPIMTSQIG IAADRFSPSK
     RWHVDTMLRV LSLAGSYVKE QILSSFIRLV ATTPDLQQYV VQKLYTALRK DITQEGLTLG
     GAWCIGEFAD LLLKGDNYEE AELVQEVKEG EVIDLFSTIL NSSYATQSAN EYIITALMKL
     STRFTEAAQI DRIRRILAGH SRSLDVEVQQ RAVEYGNLFA HDAIRRGVLE KMPPPQIKEE
     SRVLGEATKK PKKSAAAANR RSAPAKKNAS EDLLFDLMGD DSGAPQADLG AAMVGQQNTD
     LLADILGGTT SLAPSAKSGS NVNDIRNLFG ASSTTSPIVQ NTPDMFSSMS PAPTAPSPQP
     AGVLPCYSKN DLNVTLQVQR NAEGVVLVTA RFANASFTDR KSGVGLQAAV PKTQKLALNA
     ITSGELGPGQ EATQSMRITG SKGPLRLRLK ISYATPALGS LVEQVDWSEP R
//