ID L8G0V9_PSED2 Unreviewed; 545 AA.
AC L8G0V9;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Dynactin subunit 4 {ECO:0000256|ARBA:ARBA00034864};
GN ORFNames=GMDG_00373 {ECO:0000313|EMBL:ELR06757.1};
OS Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) (Bat
OS white-nose syndrome fungus) (Geomyces destructans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=658429 {ECO:0000313|EMBL:ELR06757.1, ECO:0000313|Proteomes:UP000011064};
RN [1] {ECO:0000313|Proteomes:UP000011064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4855 / 20631-21 {ECO:0000313|Proteomes:UP000011064};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C.A., Blehert D.S., Lorch J.M., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Geomyces destructans 20631-21.";
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm,
CC cytoskeleton, stress fiber {ECO:0000256|ARBA:ARBA00004529}.
CC -!- SIMILARITY: Belongs to the dynactin subunit 4 family.
CC {ECO:0000256|ARBA:ARBA00034776}.
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DR EMBL; GL573171; ELR06757.1; -; Genomic_DNA.
DR RefSeq; XP_012738764.1; XM_012883310.1.
DR AlphaFoldDB; L8G0V9; -.
DR STRING; 658429.L8G0V9; -.
DR VEuPathDB; FungiDB:GMDG_00373; -.
DR HOGENOM; CLU_034750_0_0_1; -.
DR InParanoid; L8G0V9; -.
DR OrthoDB; 5483333at2759; -.
DR Proteomes; UP000011064; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005869; C:dynactin complex; IEA:InterPro.
DR GO; GO:0001725; C:stress fiber; IEA:UniProtKB-SubCell.
DR InterPro; IPR008603; DCTN4.
DR PANTHER; PTHR13034; DYNACTIN P62 SUBUNIT; 1.
DR PANTHER; PTHR13034:SF2; DYNACTIN SUBUNIT 4; 1.
DR Pfam; PF05502; Dynactin_p62; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000011064}.
FT REGION 18..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 177..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 509..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..36
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..211
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 545 AA; 59268 MW; B1B0E17893E26AEB CRC64;
MAAAIPYTYI QCPCTRDTHH DGDREERQGD KDSVDSSEER AEEDDDFDPH NPRANYSLYP
IDHLLYCEIC AQIRCQRCLA DEIVTWFCPN CLFEVPSSTV KSEGNRCTRS CFQCPICIAP
LSLTGQGASN TLLGGADSSH WVLSCASCSW SSSEIGIQFD RPNGIYNQLS RIRNGGQVIT
PPKERALGKD TDRRPGERRS TLSKVSEHDT PESDAGEEED TDPTPEARFA SLRAFYQSQM
SSHGSTERSA FTNDYSYASP NALSRIMNLY TSYPSPTTQK RMTQVREALN TSEGLHPIPD
PASEAATILR LRKEGWAGTP STEQRAAQPF PTCDIHSTSE LRPSPYLLRT KRTKRCRTCK
HIVVRPEAKV QTSRFRMKML AASYIPTFSI RPLPTPSAPA AAAGATQLLQ PGTTHQFVLT
VRNPLYERVR VTLAAAAKTP GRVAHGVTLL CPQFEVGASR EAYADMLDEA LSGGEANAGT
GEGEAGKVYE RARNAVGVVV EVVPGVEEGF RDARSEVSGE EGEEGEEEEE GGGGGGGGAG
DSGEG
//
