ID L8G774_PSED2 Unreviewed; 693 AA.
AC L8G774;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Cyclin-like domain-containing protein {ECO:0000259|SMART:SM00385};
GN ORFNames=GMDG_03376 {ECO:0000313|EMBL:ELR08694.1};
OS Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) (Bat
OS white-nose syndrome fungus) (Geomyces destructans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=658429 {ECO:0000313|EMBL:ELR08694.1, ECO:0000313|Proteomes:UP000011064};
RN [1] {ECO:0000313|Proteomes:UP000011064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4855 / 20631-21 {ECO:0000313|Proteomes:UP000011064};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C.A., Blehert D.S., Lorch J.M., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Geomyces destructans 20631-21.";
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; GL573222; ELR08694.1; -; Genomic_DNA.
DR RefSeq; XP_012741791.1; XM_012886337.1.
DR AlphaFoldDB; L8G774; -.
DR STRING; 658429.L8G774; -.
DR VEuPathDB; FungiDB:GMDG_03376; -.
DR HOGENOM; CLU_010293_0_2_1; -.
DR InParanoid; L8G774; -.
DR OrthoDB; 5483352at2759; -.
DR Proteomes; UP000011064; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0017025; F:TBP-class protein binding; IEA:InterPro.
DR GO; GO:0070897; P:transcription preinitiation complex assembly; IEA:InterPro.
DR CDD; cd20554; CYCLIN_TFIIIB90_rpt2; 1.
DR Gene3D; 1.10.472.170; -; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 1.
DR Gene3D; 1.20.5.650; Single helix bin; 1.
DR InterPro; IPR011665; BRF1_TBP-bd_dom.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR000812; TFIIB.
DR InterPro; IPR013150; TFIIB_cyclin.
DR PANTHER; PTHR11618:SF4; TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT; 1.
DR PANTHER; PTHR11618; TRANSCRIPTION INITIATION FACTOR IIB-RELATED; 1.
DR Pfam; PF07741; BRF1; 1.
DR Pfam; PF00382; TFIIB; 2.
DR SMART; SM00385; CYCLIN; 2.
DR SUPFAM; SSF47954; Cyclin-like; 2.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Reference proteome {ECO:0000313|Proteomes:UP000011064};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 125..207
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT DOMAIN 223..307
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 344..402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 437..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 590..610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 638..693
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..39
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..388
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 452..472
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 653..693
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 693 AA; 75509 MW; 297FE1BD566E9CAA CRC64;
MGRTPNPPKV KRPNPLSTIK PIRAPTPVAR PPPPVGPAKA RRLCPNKTCP APKIEDGICK
TCGTIVEEST IVSEIQFGES SSGAAVVQGS FVGAGSGAAK SMGPAFQRAG GGTEDREKTL
REGKRIMQGF AGEHKIPESV LNSGVQIFKL AAMNNFIQGR RMNTVAAVCL YTAARKERPC
RVMLIDFADS CGVNVFKLGH TFKALHQKIS ISADGIMPVL PEDLIYRFAT KLEFGQDTTK
VAESAVRLVQ RMSLDWMVMG RRPSGICGAC LILAARMHNF RRTVKEVVYI VKVTTATIQK
RLEEFKVTAS SDLTVEQFLS NQFLESAHDP PAFYQQSESY IATKKKRKRK RHPLEGPEGD
DEESEIQRIL DSASRQSSVA SSIDPGLEIN PSGTVRRDAD GFAVPPLPAA RAIPIDPALL
ENTDNDASLN RLVAQYGEAL PPGDGPLKTS ASPGSPGKSN GKATSPTPPS AAKSVVDQAW
EEDEEEIEDE ISEMIADPHT IEHAKAFATA EQRARVHAML AYAQAPQVSI PMTASVDESE
FADDPEVANC LLSEAEAAIK EHIWVNANKD WLRDQAVKLY NQKIADKAPK ARRNRVKRPR
IGEGQTRAAS SPAEAAVEVL KERTWSKRIN YDAIRGIFEG PGSKATSVAP SVEEVEEEGD
AESTAEDYRL EEEEDVDVDV DEGWEEGMED EEF
//
