ID L8G7F1_PSED2 Unreviewed; 560 AA.
AC L8G7F1;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Methyltransferase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=GMDG_03710 {ECO:0000313|EMBL:ELR09130.1};
OS Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) (Bat
OS white-nose syndrome fungus) (Geomyces destructans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=658429 {ECO:0000313|EMBL:ELR09130.1, ECO:0000313|Proteomes:UP000011064};
RN [1] {ECO:0000313|Proteomes:UP000011064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4855 / 20631-21 {ECO:0000313|Proteomes:UP000011064};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C.A., Blehert D.S., Lorch J.M., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Geomyces destructans 20631-21.";
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL573230; ELR09130.1; -; Genomic_DNA.
DR RefSeq; XP_012742127.1; XM_012886673.1.
DR AlphaFoldDB; L8G7F1; -.
DR STRING; 658429.L8G7F1; -.
DR VEuPathDB; FungiDB:GMDG_03710; -.
DR HOGENOM; CLU_017375_6_0_1; -.
DR InParanoid; L8G7F1; -.
DR OrthoDB; 197898at2759; -.
DR Proteomes; UP000011064; Unassembled WGS sequence.
DR GO; GO:0016274; F:protein-arginine N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 2.70.160.11; Hnrnp arginine n-methyltransferase1; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR049482; ANM3-like_C2H2_Zf.
DR InterPro; IPR025799; Arg_MeTrfase.
DR InterPro; IPR041698; Methyltransf_25.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR PANTHER; PTHR11006; PROTEIN ARGININE N-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11006:SF116; PROTEIN METHYLTRANSFERASE; 1.
DR Pfam; PF21137; ANM3_C2H2_Zf; 1.
DR Pfam; PF13649; Methyltransf_25; 1.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51678; SAM_MT_PRMT; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01015}; Reference proteome {ECO:0000313|Proteomes:UP000011064};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01015};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01015}.
FT DOMAIN 87..131
FT /note="Protein arginine N-methyltransferase 3-like C2H2
FT zinc finger"
FT /evidence="ECO:0000259|Pfam:PF21137"
FT DOMAIN 259..356
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13649"
FT REGION 1..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 198..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..53
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 560 AA; 63328 MW; EC15D581AA9704B9 CRC64;
MENATDLAVS QAPEPADTSA APRSPSHSGS DTSDVDLNED DEGWEDAEPE EEQDQIVSLF
DDKVFTDVPS MLLYCKEKYG FDFLEIRNKF SLDFYGSIKL VNYIRTAVRN GQTTLAEVAK
ADFEDDKFMI PVLQDDALLF NLDDLPPASK QGDEPVADDR NLLVRVAELE EELRKTQFQF
EDYRSVVKKT LTDKWNDTSA DKNTALSEPP AEKRDDDSHY FTSYSYNDIH ETMLRDTVRT
DAYRDFIYQN KHLFKGKVVL DVGCGTGILS LFCAKAGAAK VIAVDNSDII DKARENIFNN
GFADIITCLR GKVEEVALPV EKVDIIVSEW MGYCLLYEAM LDSVIWARDK YLKPDGLMVP
SHMNMWVAPV SDADYVADHF TFWRDVYGFD MKAMMAGIRE DAQVLHMPGS TICGDAFPFL
QLSLHTTTVK DLVFTRPWKT TFTSDIDRLD GFDIWFDTFF MPSGRDVVPV DARAEDWTKQ
EEKGVAFTTG PFGKETHWRQ GVMFIDHEGA KSSRSFAVGG TLEGSLEYAV PEDNSRALDV
KFSWASGPDK KTTTQTWKMR
//
