ID L8GCB5_PSED2 Unreviewed; 645 AA.
AC L8GCB5;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 03-MAY-2023, entry version 48.
DE RecName: Full=Calponin-homology (CH) domain-containing protein {ECO:0000259|PROSITE:PS50021};
GN ORFNames=GMDG_04162 {ECO:0000313|EMBL:ELR09676.1};
OS Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) (Bat
OS white-nose syndrome fungus) (Geomyces destructans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=658429 {ECO:0000313|EMBL:ELR09676.1, ECO:0000313|Proteomes:UP000011064};
RN [1] {ECO:0000313|Proteomes:UP000011064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4855 / 20631-21 {ECO:0000313|Proteomes:UP000011064};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C.A., Blehert D.S., Lorch J.M., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Geomyces destructans 20631-21.";
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL573241; ELR09676.1; -; Genomic_DNA.
DR RefSeq; XP_012742582.1; XM_012887128.1.
DR AlphaFoldDB; L8GCB5; -.
DR STRING; 658429.L8GCB5; -.
DR VEuPathDB; FungiDB:GMDG_04162; -.
DR HOGENOM; CLU_015284_3_0_1; -.
DR InParanoid; L8GCB5; -.
DR OrthoDB; 5475188at2759; -.
DR Proteomes; UP000011064; Unassembled WGS sequence.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0051017; P:actin filament bundle assembly; IEA:InterPro.
DR CDD; cd21294; CH_FIMB_rpt1; 1.
DR CDD; cd21297; CH_FIMB_rpt2; 1.
DR CDD; cd21300; CH_FIMB_rpt3; 1.
DR CDD; cd21303; CH_FIMB_rpt4; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 4.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR039959; Fimbrin/Plastin.
DR PANTHER; PTHR19961:SF18; FI19014P1; 1.
DR PANTHER; PTHR19961; FIMBRIN/PLASTIN; 1.
DR Pfam; PF00307; CH; 4.
DR SMART; SM00033; CH; 4.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 4.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000011064};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 137..258
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 286..389
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 410..520
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 535..643
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 84..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 645 AA; 72372 MW; C028BE39CD86E185 CRC64;
MNVIKLQRKF PEFQQDEIFG LQDAFRKLDE DDKGYIDEGT AIKATQQSER QPYDVVRQAL
KEVELDSSRR VELEDYVGLV SKLRESSPAQ KRMSTGPSRP APPSSQKPTM GHASKPSASG
RIQVQGSSAN VTHTINEDER TEFTRHINAV LVGDPDVGHL LPFPTDTFEM FDKCKDGLVL
AKLINDSVPD TIDERVLNRS GKKIKTLNAF HMTENNNIVI ESAKGIGCSV VNIGSGDIIE
VREHLILGLI WQVIRRGLLG KIDIKLHPEL YRLLEEDETL EQFLRLAPEQ ILLRWFNYHL
KAANWPRRVT NFSTDIKDGE NYTVLLNQIA PETCSRSPLQ TRDLLQRAEE VLQNADRLEC
RKFLSPTSLV AGNPKLNLAF VANLFNTHPA LDPITEEEKL QVDDFDAEGE REARVFTLWL
NSLDVNPSVN SLFDDLRDGT VLLQAYDKVI KGSVNWKHVN NAPASGAEIS RFKAVENTNY
AIELGKQNRF SLVGIQGADI TDGQKTLTLG LVWQLMRKDI SETLSDLAQR MGKREITDAE
MVKWANDMSR KGGKSSAIRS FKDSSIGTGT FLLDVLNGMK SSYVDYDLVT SGRTEDEAYL
NAKLSISIAR KLGATIWLVP EDICQIRSRL VVTFIGSLMA THDKM
//
