ID   L8GD94_PSED2            Unreviewed;       576 AA.
AC   L8GD94;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELR10066.1};
GN   ORFNames=GMDG_04467 {ECO:0000313|EMBL:ELR10066.1};
OS   Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) (Bat
OS   white-nose syndrome fungus) (Geomyces destructans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=658429 {ECO:0000313|EMBL:ELR10066.1, ECO:0000313|Proteomes:UP000011064};
RN   [1] {ECO:0000313|Proteomes:UP000011064}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4855 / 20631-21 {ECO:0000313|Proteomes:UP000011064};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C.A., Blehert D.S., Lorch J.M., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA   Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA   Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA   Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The genome sequence of Geomyces destructans 20631-21.";
RL   Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC       {ECO:0000256|ARBA:ARBA00006432}.
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DR   EMBL; GL573249; ELR10066.1; -; Genomic_DNA.
DR   RefSeq; XP_012742888.1; XM_012887434.1.
DR   AlphaFoldDB; L8GD94; -.
DR   STRING; 658429.L8GD94; -.
DR   VEuPathDB; FungiDB:GMDG_04467; -.
DR   HOGENOM; CLU_000022_59_5_1; -.
DR   InParanoid; L8GD94; -.
DR   OrthoDB; 2596785at2759; -.
DR   Proteomes; UP000011064; Unassembled WGS sequence.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43859; ACYL-ACTIVATING ENZYME; 1.
DR   PANTHER; PTHR43859:SF4; BUTANOATE--COA LIGASE AAE1; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000011064}.
FT   DOMAIN          39..430
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          481..557
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   576 AA;  63820 MW;  F660D406DDFA9F07 CRC64;
     MSGAPSRLQK LAAHFLPSST QETFTHRLNN HELSPTFFLE RAAQIEPDAE AIHHTTANNV
     VLRRTYQEFA DRSRGFAYYL VKKQYKRVGI LCPNTPAFLE SIFGIGAAGA VNVGVNYRLK
     SEDIAYIFNH AEVEVIIVDA EYLHLLDRFK ELYPQIPFII DTDTDAVEEI SGPFDAAVLE
     GLSYDKETGG NGWAGLKSQC DDEQATIALA YTSGTTAKPK GVVYNHRGAY LAALANVVES
     GLNYHTGRCG YLWTLPMFHA MGWTFPWAVT AVRGTHYCMR KIDYPAIWHL LKTENVTHFN
     AAPTVNTLLC ASPEAERLEK PVRVTVAASP PTAHLFKTME SLNLMPVHVY GLTETYGPIT
     KGYRMPAWEN LPENEKYDKM ARQGHGAITT LPCRVIKTEQ APGIIVDVKK DGKEIGEIVF
     LGNICAKEYY KDPEATRKIF DGGVLHSGDL AVWHADGAIQ ILDRAKDIII SGGENISSVS
     LEGMLVQHPD VLEAGVVAVP DSHWGERPKA FVTVQQGKTL KGDDVIQWAK HKSDISKFMV
     PREVEIVAEL PKTSTGKVKK NVLRIWAKGT DRSTDL
//