ID L8HNU8_9CETA Unreviewed; 464 AA.
AC L8HNU8;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Protein ERGIC-53 {ECO:0000313|EMBL:ELR45551.1};
DE Flags: Fragment;
GN ORFNames=M91_18504 {ECO:0000313|EMBL:ELR45551.1};
OS Bos mutus (wild yak).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=72004 {ECO:0000313|EMBL:ELR45551.1, ECO:0000313|Proteomes:UP000011080};
RN [1] {ECO:0000313|EMBL:ELR45551.1, ECO:0000313|Proteomes:UP000011080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=yakQH1 {ECO:0000313|Proteomes:UP000011080};
RX PubMed=22751099; DOI=10.1038/ng.2343;
RA Qiu Q., Zhang G., Ma T., Qian W., Wang J., Ye Z., Cao C., Hu Q., Kim J.,
RA Larkin D.M., Auvil L., Capitanu B., Ma J., Lewin H.A., Qian X., Lang Y.,
RA Zhou R., Wang L., Wang K., Xia J., Liao S., Pan S., Lu X., Hou H., Wang Y.,
RA Zang X., Yin Y., Ma H., Zhang J., Wang Z., Zhang Y., Zhang D., Yonezawa T.,
RA Hasegawa M., Zhong Y., Liu W., Zhang Y., Huang Z., Zhang S., Long R.,
RA Yang H., Wang J., Lenstra J.A., Cooper D.N., Wu Y., Wang J., Shi P.,
RA Wang J., Liu J.;
RT "The yak genome and adaptation to life at high altitude.";
RL Nat. Genet. 44:946-949(2012).
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DR EMBL; JH884064; ELR45551.1; -; Genomic_DNA.
DR AlphaFoldDB; L8HNU8; -.
DR STRING; 72004.ENSBMUP00000024573; -.
DR Proteomes; UP000011080; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd06902; lectin_ERGIC-53_ERGL; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR005052; Lectin_leg.
DR PANTHER; PTHR12223:SF32; PROTEIN ERGIC-53; 1.
DR PANTHER; PTHR12223; VESICULAR MANNOSE-BINDING LECTIN; 1.
DR Pfam; PF03388; Lectin_leg-like; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS51328; L_LECTIN_LIKE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011080};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 433..452
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..224
FT /note="L-type lectin-like"
FT /evidence="ECO:0000259|PROSITE:PS51328"
FT COILED 236..263
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ELR45551.1"
SQ SEQUENCE 464 AA; 52867 MW; 88CE6AC7568E6B5A CRC64;
SNRCFTKHTF RKSYFLEINV FSSLMAILDA IPSSDQIRIA PSLKSQRGSV WTKTKAAFEN
WELEVTFRVT GRSRIGADGL AVWYTENQGL EGPVFGSADM WNGVGIFFDS FDNDGKKNNP
AIVIIGNNGQ IHYDHQNDGA NQALSSCQRD FRNKPYPVRA KITYYQKTLT VMINNGFTPD
KNDYEFCAKV ENMIIPAQGH FGISAATGGL ADDHDVLSFL TFQLTEPGKE PPTVDKEISE
KEKEKYQEEF EHFQQELDKK KEEFQKDHPD LQGHPTDEMF ESVGDRELRQ VFEGQNRIHL
EIKQLNRQLD MILDEQRRYV SSLTEEISKR GAGAPGQTFQ QELDTVVNTQ HEILRQVNEM
KNSMSETVRL VSGIAHPGPA AGVYDTTQHF NDIKEHLHIV KRDIDSLAQR SMPSNERPKC
PELPPFPSCL STVHFVIFVV VQTVLFIGYI MYRTQQEAAA KKFF
//
