ID L8JKR4_9BACT Unreviewed; 587 AA.
AC L8JKR4;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Protease IV {ECO:0000313|EMBL:ELR68099.1};
GN ORFNames=C900_00949 {ECO:0000313|EMBL:ELR68099.1};
OS Fulvivirga imtechensis AK7.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Fulvivirgaceae;
OC Fulvivirga.
OX NCBI_TaxID=1237149 {ECO:0000313|EMBL:ELR68099.1, ECO:0000313|Proteomes:UP000011135};
RN [1] {ECO:0000313|EMBL:ELR68099.1, ECO:0000313|Proteomes:UP000011135}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AK7 {ECO:0000313|EMBL:ELR68099.1,
RC ECO:0000313|Proteomes:UP000011135};
RA Nupur N., Khatri I., Kumar R., Subramanian S., Pinnaka A.;
RT "Genome assembly of Fulvivirga imtechensis AK7.";
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S49 family.
CC {ECO:0000256|ARBA:ARBA00008683}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELR68099.1}.
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DR EMBL; AMZN01000149; ELR68099.1; -; Genomic_DNA.
DR RefSeq; WP_009583687.1; NZ_AMZN01000149.1.
DR AlphaFoldDB; L8JKR4; -.
DR STRING; 1237149.C900_00949; -.
DR PATRIC; fig|1237149.3.peg.5831; -.
DR eggNOG; COG0616; Bacteria.
DR OrthoDB; 9764363at2; -.
DR Proteomes; UP000011135; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006465; P:signal peptide processing; IEA:InterPro.
DR CDD; cd07018; S49_SppA_67K_type; 1.
DR CDD; cd07023; S49_Sppa_N_C; 1.
DR Gene3D; 6.20.330.10; -; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR004634; Pept_S49_pIV.
DR InterPro; IPR004635; Pept_S49_SppA.
DR InterPro; IPR002142; Peptidase_S49.
DR InterPro; IPR047217; S49_SppA_67K_type_N.
DR InterPro; IPR047272; S49_SppA_C.
DR NCBIfam; TIGR00705; SppA_67K; 1.
DR NCBIfam; TIGR00706; SppA_dom; 1.
DR PANTHER; PTHR33209; PROTEASE 4; 1.
DR PANTHER; PTHR33209:SF1; SERINE PROTEASE SPPA, CHLOROPLASTIC; 1.
DR Pfam; PF01343; Peptidase_S49; 2.
DR PIRSF; PIRSF001217; Protease_4_SppA; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:ELR68099.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011135};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825}.
FT DOMAIN 125..277
FT /note="Peptidase S49"
FT /evidence="ECO:0000259|Pfam:PF01343"
FT DOMAIN 372..521
FT /note="Peptidase S49"
FT /evidence="ECO:0000259|Pfam:PF01343"
FT ACT_SITE 193
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001217-1"
FT ACT_SITE 386
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR001217-1"
SQ SEQUENCE 587 AA; 65521 MW; E1399072EFD8F9F3 CRC64;
MNFLRNLLAS FLALVIFSVL AFFLFFGIVA AFVGSFSKKD VVEVADKSVL HLKLDKPISE
VEFENPLEVL PIFSGAPATI GLVQIKEAIR KAKDDDKIKG IYLEAPFVMA GMAVVEEVRD
ALEDFRSSGK FVVSYAEFYS EGGYYLASVA DHVYMHPEGF LEFNGLNTNV TFFKGLFDKL
EIEPQIFRVG DFKSAVEPFM RKDMSEENRL QLSSLINAAY KNVIDNIAES RNVASARLME
ISNNMLARKP QQGVEFKLLD SLVYMDQVLA VMKEKAGTSQ DEELELIKYE KYKKTVSKYN
KSKNEIAVIV ASGEIVPDKG DINTIGSTKF SEEIRKARED DNIKAIVIRI NSPGGSFVAS
DVMWREIKLA GESKPVIASM SDVAASGGYY MAMACDTIVA QPNTITGSIG IFGIIFNLQG
FLNHKLGITH DEVQTGKYSG LYTMVRPLTE QEKQIIQDDV EDGYETFITK AAEGRDMTVD
EIKKIASGRV WTGDQAKNNG LVDILGDLDD AIKIAAGKAN LGDDYKVKYY PKQRTIFEEI
LRDLEGDTQA KAIKKELGEF YPYLEAIKNV QKQEGIQTKM LYEFNLD
//
