ID L8K252_9BACT Unreviewed; 379 AA.
AC L8K252;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Cystathionine gamma-lyase {ECO:0000313|EMBL:ELR73532.1};
GN ORFNames=C900_02617 {ECO:0000313|EMBL:ELR73532.1};
OS Fulvivirga imtechensis AK7.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Fulvivirgaceae;
OC Fulvivirga.
OX NCBI_TaxID=1237149 {ECO:0000313|EMBL:ELR73532.1, ECO:0000313|Proteomes:UP000011135};
RN [1] {ECO:0000313|EMBL:ELR73532.1, ECO:0000313|Proteomes:UP000011135}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AK7 {ECO:0000313|EMBL:ELR73532.1,
RC ECO:0000313|Proteomes:UP000011135};
RA Nupur N., Khatri I., Kumar R., Subramanian S., Pinnaka A.;
RT "Genome assembly of Fulvivirga imtechensis AK7.";
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|ARBA:ARBA00009077, ECO:0000256|RuleBase:RU362118}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELR73532.1}.
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DR EMBL; AMZN01000004; ELR73532.1; -; Genomic_DNA.
DR RefSeq; WP_009577752.1; NZ_AMZN01000004.1.
DR AlphaFoldDB; L8K252; -.
DR STRING; 1237149.C900_02617; -.
DR PATRIC; fig|1237149.3.peg.308; -.
DR eggNOG; COG0626; Bacteria.
DR OrthoDB; 9803729at2; -.
DR Proteomes; UP000011135; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR CDD; cd00614; CGS_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11808:SF92; CYSTATHIONINE GAMMA-SYNTHASE; 1.
DR PANTHER; PTHR11808; TRANS-SULFURATION ENZYME FAMILY MEMBER; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:ELR73532.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR001434-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000011135}.
FT MOD_RES 195
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ SEQUENCE 379 AA; 41837 MW; BA80B9DD529F772C CRC64;
MKFGTKAIHA GVEPDPSTGA IMTPVYQTST YVQASPGAHK GYEYSRTQNP TRDALQKSLA
ALENGSHGLC FSSGLAAIDA VIKLLNPGDE VIAANDLYGG TYRLFTKVFA KYGIKFHFVS
MEKAIDIEQH INKNTKLIWL ETPTNPMMNI IDIKAAAQIA RKHQVMLAVD NTFATPYLQN
PLDMGADIVM HSVTKYLGGH SDVVMGALIV KDKKLNDDLA FLQNSSGATP GPQDCFLVLR
GIKTLHLRMQ RHSENGRKIA EYLKTHPKVD KLYWPGLENH PNHDIAKQQM RDFGGMISFT
LKGDSQEEAF RIMERFKFFS LAESLGGVES LVNHPATMTH ASIPKEERIK VGLLDSLIRL
SVGVEDAEDL IADLESALD
//
