ID L8LW36_9CYAN Unreviewed; 407 AA.
AC L8LW36;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=geranylgeranyl diphosphate reductase {ECO:0000256|ARBA:ARBA00012380};
DE EC=1.3.1.83 {ECO:0000256|ARBA:ARBA00012380};
DE AltName: Full=Geranylgeranyl reductase {ECO:0000256|ARBA:ARBA00033069};
DE Flags: Precursor;
GN ORFNames=Xen7305DRAFT_00015960 {ECO:0000313|EMBL:ELS01889.1};
OS Xenococcus sp. PCC 7305.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Pleurocapsales; Xenococcaceae;
OC Xenococcus.
OX NCBI_TaxID=102125 {ECO:0000313|EMBL:ELS01889.1, ECO:0000313|Proteomes:UP000011203};
RN [1] {ECO:0000313|EMBL:ELS01889.1, ECO:0000313|Proteomes:UP000011203}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7305 {ECO:0000313|EMBL:ELS01889.1,
RC ECO:0000313|Proteomes:UP000011203};
RX PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT genome sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3 NADP(+) + phytyl diphosphate = geranylgeranyl diphosphate +
CC 3 H(+) + 3 NADPH; Xref=Rhea:RHEA:26229, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57533, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349,
CC ChEBI:CHEBI:75434; EC=1.3.1.83;
CC Evidence={ECO:0000256|ARBA:ARBA00001640};
CC -!- PATHWAY: Porphyrin-containing compound metabolism.
CC {ECO:0000256|ARBA:ARBA00023444}.
CC -!- SIMILARITY: Belongs to the geranylgeranyl reductase family. ChlP
CC subfamily. {ECO:0000256|ARBA:ARBA00006632}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELS01889.1}.
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DR EMBL; ALVZ01000214; ELS01889.1; -; Genomic_DNA.
DR RefSeq; WP_006511014.1; NZ_ALVZ01000214.1.
DR AlphaFoldDB; L8LW36; -.
DR STRING; 102125.Xen7305DRAFT_00015960; -.
DR PATRIC; fig|102125.3.peg.3861; -.
DR eggNOG; COG0644; Bacteria.
DR OrthoDB; 417034at2; -.
DR Proteomes; UP000011203; Unassembled WGS sequence.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0102067; F:geranylgeranyl diphosphate reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0045550; F:geranylgeranyl reductase activity; IEA:InterPro.
DR GO; GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR010253; BchP_ChlP_pln/prok.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR011777; Geranylgeranyl_Rdtase_fam.
DR InterPro; IPR011774; Geranylgeranyl_Rdtase_pln/cyn.
DR NCBIfam; TIGR02023; BchP-ChlP; 1.
DR NCBIfam; TIGR02028; ChlP; 1.
DR NCBIfam; TIGR02032; GG-red-SF; 1.
DR PANTHER; PTHR42685; GERANYLGERANYL DIPHOSPHATE REDUCTASE; 1.
DR PANTHER; PTHR42685:SF4; GERANYLGERANYL DIPHOSPHATE REDUCTASE, CHLOROPLASTIC; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Chlorophyll biosynthesis {ECO:0000256|ARBA:ARBA00023171};
KW Photosynthesis {ECO:0000256|ARBA:ARBA00022531};
KW Reference proteome {ECO:0000313|Proteomes:UP000011203}.
FT DOMAIN 4..307
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
SQ SEQUENCE 407 AA; 44486 MW; A57F7F3A3301F199 CRC64;
MGIRVAVVGS GPAGSSAAEI LAKAGIETFL FERKLDNAKP CGGAIPLCMV DEFDLPPEII
DRQVRKMKMI SPSNVEVNIG HTLKDGEYIG MCRREVLDGF LRDRAAKLGA NLINGTVYQL
DVPTNDKDPY TLHYADHSNG SSKGVMKTLK ADVVIGADGA NSRIAKAIDA GDYNYAIAFQ
ERIRLPEDKM AYYEDLAEMY VGNDVSTDFY AWVFPKFDHV AVGTGTMKVH KATIKDLQAG
IRARAARKLE GGEIIKVEAH PIPEHPRPRP IRGRVVLVGD ALGTVTKSSG EGIYFAAKSA
RMCAETIVEA SQNGAKLPTE ADLKGFLKKW NKQYGATYLV LDILQKVFYR SDATREAFVE
MCADVDVQKM TFDSYLYKTV VPANPLTQMK ITAKTIGSLI RGNALAP
//
