ID L8LXW7_9CYAN Unreviewed; 387 AA.
AC L8LXW7;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=IMP dehydrogenase family protein {ECO:0000313|EMBL:ELS01718.1};
GN ORFNames=Xen7305DRAFT_00014230 {ECO:0000313|EMBL:ELS01718.1};
OS Xenococcus sp. PCC 7305.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Pleurocapsales; Xenococcaceae;
OC Xenococcus.
OX NCBI_TaxID=102125 {ECO:0000313|EMBL:ELS01718.1, ECO:0000313|Proteomes:UP000011203};
RN [1] {ECO:0000313|EMBL:ELS01718.1, ECO:0000313|Proteomes:UP000011203}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7305 {ECO:0000313|EMBL:ELS01718.1,
RC ECO:0000313|Proteomes:UP000011203};
RX PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT genome sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
CC -!- SIMILARITY: Belongs to the IMPDH/GMPR family.
CC {ECO:0000256|ARBA:ARBA00005502}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELS01718.1}.
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DR EMBL; ALVZ01000217; ELS01718.1; -; Genomic_DNA.
DR RefSeq; WP_006511164.1; NZ_ALVZ01000217.1.
DR AlphaFoldDB; L8LXW7; -.
DR STRING; 102125.Xen7305DRAFT_00014230; -.
DR PATRIC; fig|102125.3.peg.4013; -.
DR eggNOG; COG0516; Bacteria.
DR OrthoDB; 9805398at2; -.
DR Proteomes; UP000011203; Unassembled WGS sequence.
DR GO; GO:0003938; F:IMP dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR CDD; cd00381; IMPDH; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR005990; IMP_DH.
DR InterPro; IPR005992; IMP_DH-rel2.
DR InterPro; IPR001093; IMP_DH_GMPRt.
DR NCBIfam; TIGR01304; IMP_DH_rel_2; 1.
DR PANTHER; PTHR11911:SF111; INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11911; INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED; 1.
DR Pfam; PF00478; IMPDH; 1.
DR SMART; SM01240; IMPDH; 1.
DR SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000011203}.
FT DOMAIN 14..296
FT /note="IMP dehydrogenase/GMP reductase"
FT /evidence="ECO:0000259|Pfam:PF00478"
SQ SEQUENCE 387 AA; 40255 MW; EA5C93B91D32DBD6 CRC64;
MEISIGRGKK ARRAYGFDEI ALTPGVRTLD PSLADTTWEI GGIKREIPII ASAMDGVVDV
KMAALLSELG SMGVLNLEGI QTRYEDPEPI LERIASVGKE EFVGLMQELY AEPIKPELIK
QRIVQIKQQN GIAAVSLTPA GAGKYGKVVA EAGADMLFVQ ATVVSTDHLS PESITPLDLA
AFCQEMPIPV VLGNCVTYEV TLELMKAGAA GVLVGIGPGA ACTSRGVLGV GVPQATATAD
CAAARDDFYA ETGKYIPVIA DGGIITGGDI CKCLACGADA VMIGSPIARA AEAPGGDFHW
GMATPSPVLP RGTRIKVGTT GTIKEILVGP AKLDDGTHNL LGAIKTSMGT LGAKDIKDMQ
QVEVVIAPSL LTEGKVYQKA QQLGMGK
//
