ID L8MUA2_9CYAN Unreviewed; 780 AA.
AC L8MUA2;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=Pse7429DRAFT_3941 {ECO:0000313|EMBL:ELS31041.1};
OS Pseudanabaena biceps PCC 7429.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Pseudanabaenales;
OC Pseudanabaenaceae; Pseudanabaena.
OX NCBI_TaxID=927668 {ECO:0000313|EMBL:ELS31041.1, ECO:0000313|Proteomes:UP000011201};
RN [1] {ECO:0000313|EMBL:ELS31041.1, ECO:0000313|Proteomes:UP000011201}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7429 {ECO:0000313|EMBL:ELS31041.1,
RC ECO:0000313|Proteomes:UP000011201};
RX PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT genome sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SIMILARITY: In the N-terminal section; belongs to the phytochrome
CC family. {ECO:0000256|ARBA:ARBA00006402}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELS31041.1}.
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DR EMBL; ALWB01000215; ELS31041.1; -; Genomic_DNA.
DR RefSeq; WP_009628882.1; NZ_ALWB01000215.1.
DR AlphaFoldDB; L8MUA2; -.
DR PATRIC; fig|927668.3.peg.4360; -.
DR OrthoDB; 9760752at2; -.
DR Proteomes; UP000011201; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR GO; GO:0009584; P:detection of visible light; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.270; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013654; PAS_2.
DR InterPro; IPR016132; Phyto_chromo_attachment.
DR InterPro; IPR001294; Phytochrome.
DR InterPro; IPR013515; Phytochrome_cen-reg.
DR InterPro; IPR043150; Phytochrome_PHY_sf.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08446; PAS_2; 1.
DR Pfam; PF00360; PHY; 1.
DR PRINTS; PR01033; PHYTOCHROME.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50046; PHYTOCHROME_2; 1.
PE 3: Inferred from homology;
KW Chromophore {ECO:0000256|ARBA:ARBA00022991};
KW Kinase {ECO:0000313|EMBL:ELS31041.1};
KW Photoreceptor protein {ECO:0000256|ARBA:ARBA00022543};
KW Receptor {ECO:0000256|ARBA:ARBA00022543};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Transferase {ECO:0000313|EMBL:ELS31041.1}.
FT DOMAIN 164..324
FT /note="Phytochrome chromophore attachment site"
FT /evidence="ECO:0000259|PROSITE:PS50046"
FT DOMAIN 550..778
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 780 AA; 88566 MW; DD6607117B0FBC69 CRC64;
MQPTKNNIYN SVNYNAINEI EDVDLTNCDR EPIHIPQSIQ PHGLLMVLTE PDFKIVQVST
NSLEIVGRAT EYLLDRPLAD FISSDRLEAI SKCLDRSFEH INPLAISFAT AEDVTRNFNG
IVHRAISGEI ILELEPIANS IDREFFHFYY QIKKTLTKIQ AAQNLGELCD LIVREIQDIT
GCDRVMIYRF NESGDGNIIA EVKQPDQESF LGLRYPDSDI PKQAKELYKL NWLRLIPNMD
YRPSPLIPSS QIKEIAMHPL DMSHCCLRSV SPIHIEYLKN MGVAASLTIS LIQKQNLWGL
IACHHNTPIF IPYEIRTVCE FLGQLMSTEL ANKEANENLD YKLQLKNIQS QFVERLSKAN
NFVQELVAEP ETLLNLVGAK GAAVCEGDDI TMIGQTPQLD WLKSLLSWLP KQFKQDIFVT
DNLPSLYPDA DNCQAVAAGL LAMAISKIQH RYVLWFRPEL PQTVTWAGNP NKPKRLESDG
TMTIFPRKSF EAWQEIVTGR SQPWLDCEIA GASELRQAIV DIAIRQAEDL AHINLELERS
NSELDAFAYI ASHDLKEPLR GIHNYATFLL EDYGPILQDD GADKLNTLVR LTKRMEALID
SLLKFSRLGR QELQMSPIAL DPLLSNVSEL LGMNPQWQNC EIRKIRSLPT VLGDRILLEE
IFTNLISNAF KYNDQPQKWV EIDWQIVPKL EHSDENQNPT QRFVTILIRD NGIGIRDKHL
ETVFRIFKRL HAASKYGGGT GAGLTIVKKI IERHGGTIKV QSIYGQGTTF LFTLPIQESL
//
