ID L8N1K1_9CYAN Unreviewed; 633 AA.
AC L8N1K1;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Peptidoglycan glycosyltransferase {ECO:0000313|EMBL:ELS34082.1};
DE EC=2.4.1.129 {ECO:0000313|EMBL:ELS34082.1};
GN ORFNames=Pse7429DRAFT_0725 {ECO:0000313|EMBL:ELS34082.1};
OS Pseudanabaena biceps PCC 7429.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Pseudanabaenales;
OC Pseudanabaenaceae; Pseudanabaena.
OX NCBI_TaxID=927668 {ECO:0000313|EMBL:ELS34082.1, ECO:0000313|Proteomes:UP000011201};
RN [1] {ECO:0000313|EMBL:ELS34082.1, ECO:0000313|Proteomes:UP000011201}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7429 {ECO:0000313|EMBL:ELS34082.1,
RC ECO:0000313|Proteomes:UP000011201};
RX PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT genome sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELS34082.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ALWB01000020; ELS34082.1; -; Genomic_DNA.
DR RefSeq; WP_009625796.1; NZ_ALWB01000020.1.
DR AlphaFoldDB; L8N1K1; -.
DR PATRIC; fig|927668.3.peg.955; -.
DR OrthoDB; 9770103at2; -.
DR Proteomes; UP000011201; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000313|EMBL:ELS34082.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:ELS34082.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 66..175
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 253..567
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 575..633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 601..615
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 633 AA; 69674 MW; E065DFC4C8AA0B2C CRC64;
MTPSFLPRDL ATINLFKRRT VLIWIILAVA MLGLVVRLVY LQVVTSSDLL EKARRQQMFT
LRPFIPRRTI TDRKGAVLAL DRPVYTLFAY PHLYKEKPEE IAAKLAPILK RPADKLLSVL
TRDTTSIQVE YWLSEESSDR IYNLRLDGLE LIQQRHRLYP QQDLASEILG YVNVDHRGQA
GIELSQEKLL ERTDQAPSVA QQDGNGKFIP NRIPAGMINS DRTSLQMTID SRIQRTARQI
LKQQMVKFSA KRGSVIVMDV RDGGLLTLVT EPTYDPNRYY EADVKLFKNW AVSDLYEPGS
TFKPLNVAIA IEAGAIQPDT VFNDEGALTI GGWPVANFDY EQVGAVGPLS ISQILQRSSN
VGMVHIIQRM KPSVYYGWLE RIGLGDISGI DLPSETPSTL KPQEQFIEYV IEPATAAFGQ
GFSLTPIQMV QLHGILASGG KLLTPHVVKG LINEEGEEYY QPKLPTPRQV ISPATTQRVL
EMMTDVVEKG TGLPARIPGY RLAGKTGTAQ KASSTGGGYA NAKITSFVGI FPSKEPRYVV
IAVIDEPVGS DAFGSTVAAP IVKTVIEDII VSEGIPPSHP EEVISKIPTI PDPQPSASPS
PSASPTQDAI PIPNTTPNGT PSPEPKPSRD RQQ
//
