ID L8N355_9CYAN Unreviewed; 721 AA.
AC L8N355;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=Pse7429DRAFT_0129 {ECO:0000313|EMBL:ELS34672.1};
OS Pseudanabaena biceps PCC 7429.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Pseudanabaenales;
OC Pseudanabaenaceae; Pseudanabaena.
OX NCBI_TaxID=927668 {ECO:0000313|EMBL:ELS34672.1, ECO:0000313|Proteomes:UP000011201};
RN [1] {ECO:0000313|EMBL:ELS34672.1, ECO:0000313|Proteomes:UP000011201}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7429 {ECO:0000313|EMBL:ELS34672.1,
RC ECO:0000313|Proteomes:UP000011201};
RX PubMed=23277585; DOI=10.1073/pnas.1217107110;
RA Shih P.M., Wu D., Latifi A., Axen S.D., Fewer D.P., Talla E., Calteau A.,
RA Cai F., Tandeau de Marsac N., Rippka R., Herdman M., Sivonen K.,
RA Coursin T., Laurent T., Goodwin L., Nolan M., Davenport K.W., Han C.S.,
RA Rubin E.M., Eisen J.A., Woyke T., Gugger M., Kerfeld C.A.;
RT "Improving the coverage of the cyanobacterial phylum using diversity-driven
RT genome sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:1053-1058(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELS34672.1}.
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DR EMBL; ALWB01000004; ELS34672.1; -; Genomic_DNA.
DR RefSeq; WP_009625138.1; NZ_ALWB01000004.1.
DR AlphaFoldDB; L8N355; -.
DR PATRIC; fig|927668.3.peg.199; -.
DR OrthoDB; 9773246at2; -.
DR Proteomes; UP000011201; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43065:SF50; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF12860; PAS_7; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:ELS34672.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000313|EMBL:ELS34672.1}.
FT DOMAIN 228..280
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 446..718
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 407..437
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 721 AA; 80935 MW; A697ABEB33E1F26C CRC64;
MAKANPKAQW GTILTRANHA EKYLRWFVEF CPVPIAMFDR DMNYILVSQP WVKMLGIPRL
KLIGTNLYDS LPRAIAHKNG LERCLSGGQM HYVGEIEIMT RGESAHTFQW NVQTWYGDDG
SAGGIIIASQ ALTDPLSSSL KQQLAEEIEE RRYLEDAFTK IGTAIESAND AICITDETGK
PIYINLAFSD LFAYDLSALQ EDQNFACLFA DIETSQIIHK AVMRGGNWSS ELHMRDRHRQ
DVPMALRVNP VKNPSGQVIG TTYVCTNISD RQVAEAEINK SFAALGATLE ATADGILVLD
ECSNITICNQ KFVELWRIPD RIFTSHNDTQ ILEYVTQRIT SSQYLHNFGK ELRGDQNSFE
VVELDDGRTL ECYSQPQHVL DGRAGRVWSL RDITERLAAE ALVRASEEKY RLQAEKLEYA
LQELKSTQSQ LIQAEKMSGL GQLVAGIAHE INNPVNFIYG NLSYADTYTA DLLSLVEAYR
VNYPTPVEPV QAKLQEIDID FLAQDFTKLI GSIRLGAERI HRIVLSLNKF SRSDEAGAKY
VDIHEGIDST LMILQSRIKS TPSRPEILIK RDYGDLPEVE CYAGQLNQVF MNLLTNAIDA
LESDAEHNGM WQMVNDKPQW TRKDGKVSTI LIRTEILNNQ SHGDRLVVTI ADNGSGIPED
IRNRLFDLFF TTKPVGKGTG LGLSIAYQIV TENHGGKLSF RSEVGIGTEF TIEIPLKQLQ
N
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