ID L8TLI6_9MICC Unreviewed; 548 AA.
AC L8TLI6;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=G205_13652 {ECO:0000313|EMBL:ELT44163.1};
OS Arthrobacter nitrophenolicus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=683150 {ECO:0000313|EMBL:ELT44163.1, ECO:0000313|Proteomes:UP000011189};
RN [1] {ECO:0000313|Proteomes:UP000011189}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SJCon {ECO:0000313|Proteomes:UP000011189};
RX PubMed=23516196; DOI=10.1128/genomeA.00058-13;
RA Vikram S., Kumar S., Vaidya B., Pinnaka A.K., Raghava G.P.;
RT "Draft Genome Sequence of the 2-Chloro-4-Nitrophenol-Degrading Bacterium
RT Arthrobacter sp. Strain SJCon.";
RL Genome Announc. 1:e0005813-e0005813(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RAD25/XPB subfamily.
CC {ECO:0000256|ARBA:ARBA00006637}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELT44163.1}.
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DR EMBL; AOFD01000029; ELT44163.1; -; Genomic_DNA.
DR RefSeq; WP_009358148.1; NZ_AOFD01000029.1.
DR AlphaFoldDB; L8TLI6; -.
DR PATRIC; fig|683150.5.peg.2679; -.
DR Proteomes; UP000011189; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd18029; DEXHc_XPB; 1.
DR CDD; cd18789; SF2_C_XPB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR032438; ERCC3_RAD25_C.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032830; XPB/Ssl2_N.
DR PANTHER; PTHR11274:SF0; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB; 1.
DR PANTHER; PTHR11274; RAD25/XP-B DNA REPAIR HELICASE; 1.
DR Pfam; PF16203; ERCC3_RAD25_C; 1.
DR Pfam; PF13625; Helicase_C_3; 1.
DR Pfam; PF04851; ResIII; 1.
DR PRINTS; PR00851; XRODRMPGMNTB.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|EMBL:ELT44163.1};
KW Helicase {ECO:0000313|EMBL:ELT44163.1};
KW Hydrolase {ECO:0000313|EMBL:ELT44163.1};
KW Nucleotide-binding {ECO:0000313|EMBL:ELT44163.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011189}.
FT DOMAIN 190..344
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 395..545
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 548 AA; 60807 MW; CA5C6DECEF2C4168 CRC64;
MNDGPLIVQS DKTILLEVDH ELATEARHAI APFAELERAP EHMHSYRLTP LGLWNARAAG
LDAEKVLDTL LKYSRFPVPH SLLIDIEETM SRYGRLRLEK DPQHGLVMRT DDYPVLEEVI
RAKKIQPLLG PRIDGETVVV HASQRGQLKQ LLLKIGWPAE DLAGYVDGTP HLIALNEDGW
QLRPYQRLAS ENFWAGGSGV VVLPCGAGKT LVGAAAMATG STTTLILVTN TVAARQWKDE
LLKRTSLTAD EIGEYSGAVK EVRPVTIATY QVLTTRRGGL YPHLELVDGH DWGLIIYDEV
HLLPAPIFRM TADLQARRRL GLTATLVRED GREGEVFSLI GPKRYDAPWK DIESQGYIAP
ADCVEVRVDL SKDERVAYAM ADDADKYRLC STSESKTQVV EELVARHAGE QLLVIGQYID
QLDDLGGRLG APVIKGDTSV KVRQRLFDEF RAGDIQTLVV SKVANFSIDL PEASVAIQVS
GSFGSRQEEA QRLGRLLRPK KDGRAARFYS LVARDTLDQD FAAKRQRFLA EQGYAYRIMD
AKDVGQPG
//
