ID L8TPM3_9MICC Unreviewed; 161 AA.
AC L8TPM3;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Fe2+/Zn2+ uptake regulation protein {ECO:0000313|EMBL:ELT45228.1};
DE SubName: Full=Transcriptional repressor {ECO:0000313|EMBL:TDL41251.1};
GN ORFNames=E2R57_00835 {ECO:0000313|EMBL:TDL41251.1}, G205_06873
GN {ECO:0000313|EMBL:ELT45228.1};
OS Arthrobacter nitrophenolicus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=683150 {ECO:0000313|EMBL:ELT45228.1, ECO:0000313|Proteomes:UP000011189};
RN [1] {ECO:0000313|EMBL:ELT45228.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SJCon {ECO:0000313|EMBL:ELT45228.1};
RA Vikram S., Kumar S., Vaidya B., Pinnaka A.K., Raghava G.P.S.;
RT "Draft Genome Sequence of the 2-Chloro-4-Nitrophenol-Degrading Bacterium
RT Arthrobacter sp. Strain SJCon.";
RL Genome Announc. 1:E00058-13(2013).
RN [2] {ECO:0000313|Proteomes:UP000011189}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SJCon {ECO:0000313|Proteomes:UP000011189};
RX PubMed=23516196; DOI=10.1128/genomeA.00058-13;
RA Vikram S., Kumar S., Vaidya B., Pinnaka A.K., Raghava G.P.;
RT "Draft Genome Sequence of the 2-Chloro-4-Nitrophenol-Degrading Bacterium
RT Arthrobacter sp. Strain SJCon.";
RL Genome Announc. 1:e0005813-e0005813(2013).
RN [3] {ECO:0000313|EMBL:TDL41251.1, ECO:0000313|Proteomes:UP000294621}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S-A1 {ECO:0000313|EMBL:TDL41251.1,
RC ECO:0000313|Proteomes:UP000294621};
RA Steinbock B., Bechtold R., Sevigny J.L., Thomas D., Cuthill L.R.,
RA Aveiro Johannsen E.J., Thomas K., Ghosh A.;
RT "Genome Sequencing and Assembly of Various Microbes Isolated from Partially
RT Reclaimed Soil and Acid Mine Drainage (AMD) Site.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|PIRSR:PIRSR602481-1};
CC Note=Binds 1 zinc ion per subunit. {ECO:0000256|PIRSR:PIRSR602481-1};
CC -!- SIMILARITY: Belongs to the Fur family. {ECO:0000256|ARBA:ARBA00007957}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELT45228.1}.
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DR EMBL; AOFD01000011; ELT45228.1; -; Genomic_DNA.
DR EMBL; SMZQ01000001; TDL41251.1; -; Genomic_DNA.
DR RefSeq; WP_009357172.1; NZ_SMZQ01000001.1.
DR AlphaFoldDB; L8TPM3; -.
DR SMR; L8TPM3; -.
DR STRING; 683150.G205_06873; -.
DR PATRIC; fig|683150.5.peg.1373; -.
DR OrthoDB; 5242893at2; -.
DR Proteomes; UP000011189; Unassembled WGS sequence.
DR Proteomes; UP000294621; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd07153; Fur_like; 1.
DR Gene3D; 3.30.1490.190; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR002481; FUR.
DR InterPro; IPR043135; Fur_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR33202:SF18; TRANSCRIPTIONAL REGULATOR FURA; 1.
DR PANTHER; PTHR33202; ZINC UPTAKE REGULATION PROTEIN; 1.
DR Pfam; PF01475; FUR; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR602481-1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011189};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PIRSR:PIRSR602481-1}.
FT BINDING 98
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
FT BINDING 101
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
FT BINDING 141
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
FT BINDING 144
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
SQ SEQUENCE 161 AA; 17900 MW; BD38049DA4113525 CRC64;
MTEHHDGHED WAGALRAHGR RVTKQRLAVL AAVERHPHSP AESILAAARA ELPELTAQSV
YVVLGDLTDL HMLRRFEPPH SPALYETRVG DNHHHAICIS CGRVEDVDCA VGHAPCLTPH
WDENAKPMTI QIADVMYQGI CQDCQQSQQL PSNRPSQVTE K
//
