ID L8TSS5_9MICC Unreviewed; 438 AA.
AC L8TSS5;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=Thymidine phosphorylase {ECO:0000313|EMBL:ELT44304.1};
DE EC=2.4.2.4 {ECO:0000313|EMBL:ELT44304.1};
GN Name=deoA {ECO:0000313|EMBL:ELT44304.1};
GN ORFNames=E2R57_17160 {ECO:0000313|EMBL:TDL33638.1}, G205_12982
GN {ECO:0000313|EMBL:ELT44304.1};
OS Arthrobacter nitrophenolicus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=683150 {ECO:0000313|EMBL:ELT44304.1, ECO:0000313|Proteomes:UP000011189};
RN [1] {ECO:0000313|EMBL:ELT44304.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SJCon {ECO:0000313|EMBL:ELT44304.1};
RA Vikram S., Kumar S., Vaidya B., Pinnaka A.K., Raghava G.P.S.;
RT "Draft Genome Sequence of the 2-Chloro-4-Nitrophenol-Degrading Bacterium
RT Arthrobacter sp. Strain SJCon.";
RL Genome Announc. 1:E00058-13(2013).
RN [2] {ECO:0000313|Proteomes:UP000011189}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SJCon {ECO:0000313|Proteomes:UP000011189};
RX PubMed=23516196; DOI=10.1128/genomeA.00058-13;
RA Vikram S., Kumar S., Vaidya B., Pinnaka A.K., Raghava G.P.;
RT "Draft Genome Sequence of the 2-Chloro-4-Nitrophenol-Degrading Bacterium
RT Arthrobacter sp. Strain SJCon.";
RL Genome Announc. 1:e0005813-e0005813(2013).
RN [3] {ECO:0000313|EMBL:TDL33638.1, ECO:0000313|Proteomes:UP000294621}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S-A1 {ECO:0000313|EMBL:TDL33638.1,
RC ECO:0000313|Proteomes:UP000294621};
RA Steinbock B., Bechtold R., Sevigny J.L., Thomas D., Cuthill L.R.,
RA Aveiro Johannsen E.J., Thomas K., Ghosh A.;
RT "Genome Sequencing and Assembly of Various Microbes Isolated from Partially
RT Reclaimed Soil and Acid Mine Drainage (AMD) Site.";
RL Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the thymidine/pyrimidine-nucleoside
CC phosphorylase family. {ECO:0000256|ARBA:ARBA00006915}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELT44304.1}.
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DR EMBL; AOFD01000026; ELT44304.1; -; Genomic_DNA.
DR EMBL; SMZQ01000010; TDL33638.1; -; Genomic_DNA.
DR RefSeq; WP_009358037.1; NZ_SMZQ01000010.1.
DR AlphaFoldDB; L8TSS5; -.
DR STRING; 683150.G205_12982; -.
DR PATRIC; fig|683150.5.peg.2559; -.
DR OrthoDB; 9763887at2; -.
DR Proteomes; UP000011189; Unassembled WGS sequence.
DR Proteomes; UP000294621; Unassembled WGS sequence.
DR GO; GO:0004645; F:1,4-alpha-oligoglucan phosphorylase activity; IEA:InterPro.
DR GO; GO:0016154; F:pyrimidine-nucleoside phosphorylase activity; IEA:InterPro.
DR GO; GO:0009032; F:thymidine phosphorylase activity; IEA:UniProtKB-EC.
DR GO; GO:0006206; P:pyrimidine nucleobase metabolic process; IEA:InterPro.
DR GO; GO:0006213; P:pyrimidine nucleoside metabolic process; IEA:InterPro.
DR Gene3D; 3.40.1030.10; Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain; 1.
DR Gene3D; 3.90.1170.30; Pyrimidine nucleoside phosphorylase-like, C-terminal domain; 1.
DR InterPro; IPR000312; Glycosyl_Trfase_fam3.
DR InterPro; IPR017459; Glycosyl_Trfase_fam3_N_dom.
DR InterPro; IPR036320; Glycosyl_Trfase_fam3_N_dom_sf.
DR InterPro; IPR035902; Nuc_phospho_transferase.
DR InterPro; IPR036566; PYNP-like_C_sf.
DR InterPro; IPR013102; PYNP_C.
DR InterPro; IPR018090; Pyrmidine_PPas_bac/euk.
DR InterPro; IPR017872; Pyrmidine_PPase_CS.
DR InterPro; IPR000053; Thymidine/pyrmidine_PPase.
DR NCBIfam; TIGR02644; Y_phosphoryl; 1.
DR PANTHER; PTHR10515; THYMIDINE PHOSPHORYLASE; 1.
DR PANTHER; PTHR10515:SF0; THYMIDINE PHOSPHORYLASE; 1.
DR Pfam; PF02885; Glycos_trans_3N; 1.
DR Pfam; PF00591; Glycos_transf_3; 1.
DR Pfam; PF07831; PYNP_C; 1.
DR PIRSF; PIRSF000478; TP_PyNP; 1.
DR SMART; SM00941; PYNP_C; 1.
DR SUPFAM; SSF52418; Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain; 1.
DR SUPFAM; SSF47648; Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain; 1.
DR SUPFAM; SSF54680; Pyrimidine nucleoside phosphorylase C-terminal domain; 1.
DR PROSITE; PS00647; THYMID_PHOSPHORYLASE; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000313|EMBL:ELT44304.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011189};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ELT44304.1}.
FT DOMAIN 348..422
FT /note="Pyrimidine nucleoside phosphorylase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00941"
SQ SEQUENCE 438 AA; 45584 MW; 60A9CF0CE4FFBC4E CRC64;
MTDSKAEAFD AVDIIRTKRD KGTLSPEQID WTIDAYTRGA IADEQMAALN MAILLNGMNR
TEIARWTAAM IASGETMDFS GLRRPDGGLK YTSDKHSTGG VGDKITLPLA PLVAVFGVAV
PQLSGRGLGH TGGTLDKLES IPGWRASLSN EEMMAQLQDV GAVICAAGAG LAPADKKLYA
LRDVTGTVEA IPLIASSIMS KKIAEGTGSL VLDVKVGSGA FMKDEASARE LAETMVALGK
DAGVNTVALL TNMDTPLGLT AGNAIEVEES VEVLAGGGPE DVVELTVRLA EEMLAAAGVH
GADPAAALKD GRAMDVWNRM IQAQGGDPRA KLPAARESET VYAPADGVLV QLDALAVGIA
AWRLGAGRAR KEDAVQAGAG VRMHAKPGAV VRAGEPLMTL LTDTPEKFAR AKEALEHAVV
IAPEGSRPAQ RLILDRIA
//
