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Database: UniProt
Entry: L8TVM6_9MICC
LinkDB: L8TVM6_9MICC
Original site: L8TVM6_9MICC 
ID   L8TVM6_9MICC            Unreviewed;       529 AA.
AC   L8TVM6;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   22-NOV-2017, entry version 27.
DE   RecName: Full=D-3-phosphoglycerate dehydrogenase {ECO:0000256|RuleBase:RU363003};
DE            EC=1.1.1.95 {ECO:0000256|RuleBase:RU363003};
GN   ORFNames=G205_02598 {ECO:0000313|EMBL:ELT45855.1};
OS   Arthrobacter nitrophenolicus.
OC   Bacteria; Actinobacteria; Micrococcales; Micrococcaceae; Arthrobacter.
OX   NCBI_TaxID=683150 {ECO:0000313|EMBL:ELT45855.1, ECO:0000313|Proteomes:UP000011189};
RN   [1] {ECO:0000313|EMBL:ELT45855.1, ECO:0000313|Proteomes:UP000011189}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SJCon {ECO:0000313|EMBL:ELT45855.1,
RC   ECO:0000313|Proteomes:UP000011189};
RA   Vikram S., Kumar S., Vaidya B., Pinnaka A.K., Raghava G.P.S.;
RT   "Draft Genome Sequence of the 2-Chloro-4-Nitrophenol-Degrading
RT   Bacterium Arthrobacter sp. Strain SJCon.";
RL   Genome Announc. 1:E00058-13(2013).
CC   -!- CATALYTIC ACTIVITY: 3-phospho-D-glycerate + NAD(+) = 3-
CC       phosphonooxypyruvate + NADH. {ECO:0000256|RuleBase:RU363003}.
CC   -!- PATHWAY: Amino-acid biosynthesis; L-serine biosynthesis; L-serine
CC       from 3-phospho-D-glycerate: step 1/3.
CC       {ECO:0000256|RuleBase:RU363003}.
CC   -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC       dehydrogenase family. {ECO:0000256|RuleBase:RU363003}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ELT45855.1}.
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DR   EMBL; AOFD01000004; ELT45855.1; -; Genomic_DNA.
DR   RefSeq; WP_009356540.1; NZ_AOFD01000004.1.
DR   EnsemblBacteria; ELT45855; ELT45855; G205_02598.
DR   PATRIC; fig|683150.5.peg.523; -.
DR   UniPathway; UPA00135; UER00196.
DR   Proteomes; UP000011189; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1330.90; -; 1.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR029009; ASB_dom_sf.
DR   InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR   InterPro; IPR029753; D-isomer_DH_CS.
DR   InterPro; IPR029752; D-isomer_DH_CS1.
DR   InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR006236; PGDH.
DR   Pfam; PF00389; 2-Hacid_dh; 1.
DR   Pfam; PF02826; 2-Hacid_dh_C; 1.
DR   Pfam; PF01842; ACT; 1.
DR   SUPFAM; SSF143548; SSF143548; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR01327; PGDH; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
DR   PROSITE; PS00670; D_2_HYDROXYACID_DH_2; 1.
DR   PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|RuleBase:RU363003};
KW   Complete proteome {ECO:0000313|Proteomes:UP000011189};
KW   NAD {ECO:0000256|RuleBase:RU363003};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU363003};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011189};
KW   Serine biosynthesis {ECO:0000256|RuleBase:RU363003}.
FT   DOMAIN      455    529       ACT. {ECO:0000259|PROSITE:PS51671}.
SQ   SEQUENCE   529 AA;  55495 MW;  89E0B6450D00CA04 CRC64;
     MSKPVVLLAE ELSPATVEAL GPDFEIRQTD GADRSQLLSA ISDVDAILVR SATQVDAEAI
     AAAKNLKVIA RAGVGLDNVD IKAATQAGVM VVNAPTSNIV SAAELTVGHI LSLARHIPQA
     SAALKDGEWK RSKYTGIELF EKKIGIIGLG RIGALVAARL KGFDTKILAY DPYITSARAA
     QLGVQLVTLD ELLAQADFIT IHMPKTPETV GMLGADAFKK MKNTAYVVNV ARGGLVDEEA
     LFTALQDGEI AGAGVDVFAK EPSTDLPFFK LDNVVVTPHL GASTDEAQEK AGVSVAKSVR
     LALAGELVPD AVNVAGGVIA PDVRPGIPLI EKLGRIFTAL THDSLTQFDV EVAGEISSLD
     VKVLELAALK GIFADVVTEQ VSYVNAPVIA EQRGINVRLI TTAETESYRN VLTLRGALSD
     GSQISVAGTL TGPKQIQKLV GINGFEVEIP ISEHVVVVGY TDRPGVIGTI GHILGMNNIN
     IAGMQVARHD QGGQVLALLT VDSSVPQQVL DAIKAGIGAD MVREVDLED
//
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