ID L8WT03_THACA Unreviewed; 2853 AA.
AC L8WT03;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Cytochrome P450 {ECO:0000313|EMBL:ELU39519.1};
GN ORFNames=AG1IA_06450 {ECO:0000313|EMBL:ELU39519.1};
OS Thanatephorus cucumeris (strain AG1-IA) (Rice sheath blight fungus)
OS (Rhizoctonia solani).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Cantharellales; Ceratobasidiaceae; Rhizoctonia; Rhizoctonia solani AG-1.
OX NCBI_TaxID=983506 {ECO:0000313|EMBL:ELU39519.1, ECO:0000313|Proteomes:UP000011668};
RN [1] {ECO:0000313|EMBL:ELU39519.1, ECO:0000313|Proteomes:UP000011668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AG-1 IA {ECO:0000313|Proteomes:UP000011668};
RX PubMed=23361014; DOI=10.1038/ncomms2427;
RA Zheng A., Lin R., Xu L., Qin P., Tang C., Ai P., Zhang D., Liu Y., Sun Z.,
RA Feng H., Wang Y., Chen Y., Liang X., Fu R., Li Q., Zhang J., Yu X., Xie Z.,
RA Ding L., Guan P., Tang J., Liang Y., Wang S., Deng Q., Li S., Zhu J.,
RA Wang L., Liu H., Li P.;
RT "The evolution and pathogenic mechanisms of the rice sheath blight
RT pathogen.";
RL Nat. Commun. 4:1424-1424(2013).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- PATHWAY: Secondary metabolite biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005179}.
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELU39519.1}.
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DR EMBL; AFRT01001736; ELU39519.1; -; Genomic_DNA.
DR STRING; 983506.L8WT03; -.
DR HOGENOM; CLU_226642_0_0_1; -.
DR OMA; KDWISHR; -.
DR Proteomes; UP000011668; Unassembled WGS sequence.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd11065; CYP64-like; 1.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR46300:SF7; P450, PUTATIVE (EUROFUNG)-RELATED; 1.
DR PANTHER; PTHR46300; P450, PUTATIVE (EUROFUNG)-RELATED-RELATED; 1.
DR Pfam; PF00067; p450; 1.
DR Pfam; PF13519; VWA_2; 1.
DR PRINTS; PR00463; EP450I.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 3: Inferred from homology;
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023033};
KW Reference proteome {ECO:0000313|Proteomes:UP000011668}.
FT DOMAIN 2421..2627
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 2853 AA; 319453 MW; 96167FC87CB499BE CRC64;
MKIVLISFRI GWDDFLGMCK YGERARGMRR LLHATINPKA MKDWWPQQEK EAYKFLRKLL
HSPEKLTAHV RHTAGATVAK LTYGYDVKDE SDEYIDKAEK TLGTFAYAST PGRFLVDYFP
LLKHIPWAPF QRAAAEWRAQ LIDFAEAPMN FVRTQLAKGC AEPSFVSSWL EDASEEDKPL
IPWAAGSIYA GGADTTVSAV STFLIAMLHH PEVQKAAQDE IDRMVGSNRL PGFTDRDSLP
YVEAIYKEVL RWQPLAPIGI PRKLALDYDD EYKGMRIPSK SHIIGNAWSM LWDSNAYQDP
EKFNPSRFLG PRLESNPEEI IFGFGRRRCP GAPVAHSSVW LSIVLTLAVY DILPPKSKDG
VALLPSLDYT VGVIRYAGES SNLGRNPGFS RDCEIASASH KSHEHWHHPS TCLAPQTVHC
YSLLLHPVGT CTQKMTNSPS SSSGPPNIFE DGRPRDIHVT SHPDSEFNHT TAKYEATQLP
PSHDYAPIAN DGHIIDIPVE DSKSLRVDKA KEGRKTNVSG YLVLDKGNNH LQANSITDDV
ASNIPTLFRL LDLYQEQGSG GLVEKVLIDQ LGLRDLLNTF LPGSYESISK IDFKSLDKHT
IDIRACGTEL IELPMWVTLL GKGSCYHRSE RPAIFALGSI FHYRPRHPTP ILLISCIGQK
TLHGMTKLFL RFGVIGLRLC DQMVALISPE QVGAMVWTPH QQSTNDHGTQ MDMFDESRMF
SFEVEKSTEQ EEGLYAVALV LKLIPDTRNM PNFKAAIQAR LVPGEEKAGI MTTLLEPPKA
VSQRRNETMF SKTLKSMIDK LQTIVLGDLT GDQLSILAEH GLRETYPVPF AQYEKRMALE
EEGRKREYDT NVKDVKEGIQ RDREQLKKLI GLLVHEHYSR LYPSLGISGL AAETESPDFE
RLREKYPELS NVSHSLKKRL KNGGIDDSEL RDLKLAWHTI RAYLLQDPSP SATDQAKFVG
DVLGGTIDSE RSLVANGKGT KHSKFSWQAA KNTFFDLVGY EAKPPATLLS DVEFVQALGP
LAAAFPAISS LTNRITACLR AYLDTLGDRL ARESLERVIN KEEKRLKDLI GTRRRHRFQD
ESQATGRTLL NDLRSLMPYD SSSRNMTFSN VDRKRSIFRS QNSAPSNFLN FHWTKNFKSS
MLGAYTLSQV AYGVNYFAYR FIQLVRDKCL VVVAGQNQFD LYIGDNVHLP NIIEKRNPKS
SFKYDRLGDP NQCIFAFDEG IRSLVLFHNA NFKGPELSLF GFDETFTSVH ARGSPFSLKE
WYDTEVKIDR ICFVSGAEEV CLIETSGRAR ILSLVTLNFR PPSIEIPGRI VEALSAPDGS
CLLTLIEAEE DGTLGHKLLV FHWASFGATN GINPIVLPIS SVGRVVTSFE GRNHIHLVSY
SLDTMKITSV GLQIKQKATE FSFRSNQTVS TTSTTETVNN CLIDCHMDVW TRFPASPPVI
RSTLSPLGRE SRKLIFASTT HMEHVENYFS QMINKFERTT CKPIDAEIRS TSIVAISDPP
SILVENTQCS RHLLGSFVVE LICLIPLQDN RFIPLKDGVW DPEHERSLLG ADVPAIINSL
SIGWYESLFQ SYMATKTAEL LDQALCIRRT KRWYAHSHGA PTDVALVDSS FTGKSYCLNH
FADTSFAGSA MRTTEGVWLS CTPTKDYLLV SLDFEGNLLP TGVFQLYIIS HNIHLGVHSI
ERSAQEDALL VLFNTAISNL SFQSSAMVLD PESNPSLFNQ SIVYPGNYYQ GCYRLRLKGY
RQRVLPEVPK DCSKGARAKF HIATSSRKSS NHPMASDQFL KLLHYVQSFA EVSRCSAYNS
QKQRHFPPQY ENPYGKNQKN LATHRAQQID RGLCIALSRG SLDVTDTHTP LKNLDTDEDI
PVSGPDVVFL VPDISGATIP SDEIKIEEAL VALINFCDPN TTIGPRHIIG DKNYVESIQQ
QLFNLLDQRL EYVRSWVQVN FRRFQSGNQD IRNVANKFEG AALGMRVAIR LCMEACSSCH
YLCSRPYRHS GEHQCGTTHL CLFSCEVLDD HPEPVGCGLA PNRCDIKAHS CGYNCHLIDK
NGCAQSCVKP LYHEGKHLCS ARLHSCGEPC SLQVLDSGYR CPGLCHIPWD EPHTRHLCNN
SNSCPLECQL CRRLCHESDH FHALNPNAVH LCGQSHSCTN LCAARGICRI ETQPSAVEEQ
FSGRHETFQY TRYTQVEQRL TCALPIPAGR LYHEGEHSHT VDANAFHYCN VRCPSCQYLC
TLPLEHPQQL HETSHGSMTT TQWAIQGTNQ DTRYELDGRS FGIGDEGAPM LCHLVCSAQG
RHVHIDYCRE PGNCIGGTEF EHIKERMYPD PERSKDWISH RLKWARSDPY SREQQSEFAK
WYDFATEAKK LIMYTLLVNS GPEHNATATA AANPSYCDLP IFHQPQVGQA APSNGYVSAD
GHRFNCTNPA RLQQAYHVTG SLSVFLASSG SMRSGDRMPL SNTPVTTLLR GRCNNRYGAV
LSALHSFWSS RETGLPTTQA RQDAYSVVTF NDSPATRIAN DFTSTTGQLL THLLQISANG
GTNFNSALKQ AQKLIQTHWN SCSPRTPVLV FLSDGLSSLD RNVVYNLCRA CVQLGKPLAF
YSVSFGPENS STPLREMVQI AREVYASAPR NTMDNIQGEP CAYYNLVDPT GGHIPRYFQF
TPQAASLVDR PIYRTVKYPA FQNGSAYRTV SLRIGRPVID AFSAPDGSCL LVVVFIRYEQ
EEYRVPTRFD GRGGVHVVPF DAMSKAITST ILQIAQKATE FSFRSDRNLI DCHLEVWARF
PVVPAVARNT LTAIYRQPRQ LIFSSPVELQ GAEDYFARMV SSFETTTRKP VGSTLMGIQV
KLTDTIGRNT AGQISEFKLG SFIVALLCLI PLQ
//
