ID L8WX09_THACA Unreviewed; 978 AA.
AC L8WX09;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=ATP-dependent RNA helicase DBP10 {ECO:0000313|EMBL:ELU42631.1};
GN ORFNames=AG1IA_03350 {ECO:0000313|EMBL:ELU42631.1};
OS Thanatephorus cucumeris (strain AG1-IA) (Rice sheath blight fungus)
OS (Rhizoctonia solani).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Cantharellales; Ceratobasidiaceae; Rhizoctonia; Rhizoctonia solani AG-1.
OX NCBI_TaxID=983506 {ECO:0000313|EMBL:ELU42631.1, ECO:0000313|Proteomes:UP000011668};
RN [1] {ECO:0000313|EMBL:ELU42631.1, ECO:0000313|Proteomes:UP000011668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AG-1 IA {ECO:0000313|Proteomes:UP000011668};
RX PubMed=23361014; DOI=10.1038/ncomms2427;
RA Zheng A., Lin R., Xu L., Qin P., Tang C., Ai P., Zhang D., Liu Y., Sun Z.,
RA Feng H., Wang Y., Chen Y., Liang X., Fu R., Li Q., Zhang J., Yu X., Xie Z.,
RA Ding L., Guan P., Tang J., Liang Y., Wang S., Deng Q., Li S., Zhu J.,
RA Wang L., Liu H., Li P.;
RT "The evolution and pathogenic mechanisms of the rice sheath blight
RT pathogen.";
RL Nat. Commun. 4:1424-1424(2013).
CC -!- FUNCTION: ATP-binding RNA helicase involved in the biogenesis of 60S
CC ribosomal subunits and is required for the normal formation of 25S and
CC 5.8S rRNAs. {ECO:0000256|ARBA:ARBA00003706}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DDX54/DBP10
CC subfamily. {ECO:0000256|ARBA:ARBA00010379}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELU42631.1}.
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DR EMBL; AFRT01000780; ELU42631.1; -; Genomic_DNA.
DR AlphaFoldDB; L8WX09; -.
DR STRING; 983506.L8WX09; -.
DR HOGENOM; CLU_003041_5_2_1; -.
DR OMA; EDQFGMM; -.
DR Proteomes; UP000011668; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR012541; DBP10_C.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR PANTHER; PTHR47959; ATP-DEPENDENT RNA HELICASE RHLE-RELATED; 1.
DR PANTHER; PTHR47959:SF8; RNA HELICASE; 1.
DR Pfam; PF08147; DBP10CT; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM01123; DBP10CT; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ELU42631.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000011668};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 93..121
FT /note="DEAD-box RNA helicase Q"
FT /evidence="ECO:0000259|PROSITE:PS51195"
FT DOMAIN 126..327
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 389..533
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 196..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 369..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 842..978
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 93..121
FT /note="Q motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00552"
FT COMPBIAS 12..29
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..211
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 375..394
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 842..856
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 882..915
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 939..958
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 959..978
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 978 AA; 107050 MW; 14C0A5A0C1F17F39 CRC64;
MAKRHAESGS ETSDIELSGS ESSDDQVDIF DALTKSGTGK GKHKQVEESD IEEEDDAQFI
QRAIEKRNKK GGTEVIKAVS SKGKLAKGAV GGALIYATGL NPSLLRSLLL RGFKTPTPIQ
RQSIPILLST PPRDLVGMAR TGSGKTLAYM VPLVQRLGGR HATAFGARAL ILVPARELAL
QVLKVGKDLV RGWHSDGGAH AGDRDADESI AETSTGKGSG QNLRWGLVVG GEGMDEQFEM
ISSNPDVIIA TPGRLLHLAV EMNLDLRSVQ YVVFDEADRL FELGFATALQ EILHRLPPSR
QTVLFSATLP KNLVEFAKAG LQDPKLVRLD SESKISSDLR MAFFSIKQEE KEAALLSLLR
DVIKVPLGEP VDDPQPEESG DKKNKTKNKI RPDIPAEPHQ TLIFTATKHH VEHISSLLTA
AGYSVAHIYG SLDQAARTHH MNRFRRGRAR ILVVTDVAAR GIDIPVLENV VNYDFPMGAR
VFVHRVGRTA RAGQKGWAWS FISHSELPYL LDLQLFLGRP LVSRLKGEAR NESAYTTNLV
LGTFLRSYID EAIESIRSLD QLDASLPSLR EVMKRGHGLY MRTQGKASTA SYARAKTMVK
DTTGTWSLAG GESEGAGIHP VFELVGNDKS NQDDSVDKEG NSETAVEAAQ LAMLKVVNGF
RPAETVFEIG TRGKQAAGAG LMKDRRKALA KAQLRVGATS TAADEDSDEV PDEGNEIGGV
ELEMANEDDI ERKRNHKDEE YFMSHYQKDA YTEKGYSLRD GATFAEQARN ATFDLTTDEA
LTGRQRHDKQ LNWDAKKKKF VKGSGEGADN VKIVKTESGA RLPATYRSGR FEEWKAKTKT
SLPKIGESES ERRFTGGTKG GRLAGKKFVH QGKTDAKPLD PLSLGYERKL RQMKKRGEKE
KAFEDDGDVG GSRGGKGSKH GKGTKNPKNA VGKRYGGKSM GRVKNELKSA DQIRKSREAM
AKKKAKNARP SKKGKGRR
//
