ID L8WZQ2_THACA Unreviewed; 1422 AA.
AC L8WZQ2;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Peroxisome assembly protein 12 {ECO:0000256|ARBA:ARBA00018980};
DE AltName: Full=Peroxin-12 {ECO:0000256|ARBA:ARBA00029692};
GN ORFNames=AG1IA_04149 {ECO:0000313|EMBL:ELU41829.1};
OS Thanatephorus cucumeris (strain AG1-IA) (Rice sheath blight fungus)
OS (Rhizoctonia solani).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Cantharellales; Ceratobasidiaceae; Rhizoctonia; Rhizoctonia solani AG-1.
OX NCBI_TaxID=983506 {ECO:0000313|EMBL:ELU41829.1, ECO:0000313|Proteomes:UP000011668};
RN [1] {ECO:0000313|EMBL:ELU41829.1, ECO:0000313|Proteomes:UP000011668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AG-1 IA {ECO:0000313|Proteomes:UP000011668};
RX PubMed=23361014; DOI=10.1038/ncomms2427;
RA Zheng A., Lin R., Xu L., Qin P., Tang C., Ai P., Zhang D., Liu Y., Sun Z.,
RA Feng H., Wang Y., Chen Y., Liang X., Fu R., Li Q., Zhang J., Yu X., Xie Z.,
RA Ding L., Guan P., Tang J., Liang Y., Wang S., Deng Q., Li S., Zhu J.,
RA Wang L., Liu H., Li P.;
RT "The evolution and pathogenic mechanisms of the rice sheath blight
RT pathogen.";
RL Nat. Commun. 4:1424-1424(2013).
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SUBUNIT: Component of the PEX2-PEX10-PEX12 retrotranslocation channel,
CC composed of PEX2, PEX10 and PEX12. {ECO:0000256|ARBA:ARBA00034505}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Peroxisome
CC membrane {ECO:0000256|ARBA:ARBA00004585}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004585}.
CC -!- SIMILARITY: Belongs to the pex2/pex10/pex12 family.
CC {ECO:0000256|ARBA:ARBA00008704}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELU41829.1}.
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DR EMBL; AFRT01000985; ELU41829.1; -; Genomic_DNA.
DR STRING; 983506.L8WZQ2; -.
DR HOGENOM; CLU_002842_0_0_1; -.
DR OMA; DDRGPDF; -.
DR Proteomes; UP000011668; Unassembled WGS sequence.
DR GO; GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016562; P:protein import into peroxisome matrix, receptor recycling; IEA:UniProt.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProt.
DR CDD; cd16451; mRING_PEX12; 1.
DR CDD; cd14483; SPX_PHO81_NUC-2_like; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR017375; PEX12.
DR InterPro; IPR006845; Pex_N.
DR InterPro; IPR004331; SPX_dom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12888:SF0; PEROXISOME ASSEMBLY PROTEIN 12; 1.
DR PANTHER; PTHR12888; PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF04757; Pex2_Pex12; 1.
DR Pfam; PF03105; SPX; 1.
DR SMART; SM00248; ANK; 7.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 4.
DR PROSITE; PS50088; ANK_REPEAT; 5.
DR PROSITE; PS51382; SPX; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW Reference proteome {ECO:0000313|Proteomes:UP000011668};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 278..314
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 330..655
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT REPEAT 687..719
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 720..752
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 788..820
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 820..852
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 854..886
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 1422 AA; 155735 MW; 06D4CA9138474FDC CRC64;
MEFLGDITGL DPNRPSLLEL IAQEQLRDTL QPAIKHYLKV HGASFAENFY GLKRRRTPAV
ETVRVNAVGI PYLRAKAHQY YEDFGGGIDS SLVDGASRPS LSQLTLADKL KNAYKSIYPW
MNLGMELWQL AHSLGYLFDK TPFHRPWLAW MGVDIRRLGS ADYVSRISKC RIFPQIEMII
ASQAMSQKSA DKDPARPSGV LALIRHYLFH SRRQLLDSLK LLLPISIFFL KFLEWWYSPS
SPARALSAPR SGPAIPPPAK LSPHPRGLGI GDLPYGICPL CHERLQNATA LPTGYAFCYR
CIYSYVEEHA RCPVTLLPAR IWHPDNISMA QFGKQIQSQQ IPGWGAYYLD YKALKKIISS
LASSQISQYD AVRPTDLLNL ASQPVQIENV PPTEVASELP DGFSTTTLSL YPGQEHDPPG
AGNVFHAHKA AFFFKLEREL EKARRGTLLG VQINSFYLLK EGELKLRLAT LLSKRKAAAK
RSGARSSGDS NIDEADGVEW RAVHEGFRLL ERDLSKLQVD FDPGTLSVIY SHAENRVLSN
STLPELYLAR QVEVQPVFNR ELIAELSDTV AACLLDLTNA SIDDSPVQPG LGSGDLMLTQ
HIALSRVRHS SAIADLEGNL NKAIQNSEPN ETHIRQLLSL AQEAITTSDK NHIIRILWRA
AIEAPRIVSD VIVDSPPFDI EAIDDISGRT FLHETALSGQ LRLVEMALAR GVDPSKLDVY
ARSALHYAAL KGHSDVCRAL LASGAPSDAL DMDNFSPIIH ATVNGHLECC SALLVDGHVN
PMSAQAGQDL APLSLACKHG HRNVVLLLLA HGATSQPNSN GELPLHLAAQ EGHDAICRLL
LRDPFQDDIP DKYNEWTPLF HAARYGRIEC VKLLLEAGHN QTALDDVGRQ PVHYATWFGH
IDCMHALSQA IHPLHGTMSK STKASSISPA SDLDAPLDFD LDADPIPTLS LPPPIMPFRV
YGHNYLDQNH LVQIALGCPW TLHDSHVLHP VAGVQLVPRL QGISSKALPQ SNPSLKLVAT
SNFSATDPSF NVVLPLSDDQ DIFSLQVKGL QNLTLEFSVY PSFGSKAIGR AVALSHSFTE
LQGTGMIILP ILDHRLHLIG QVSFDVCIIT PFSSAGFDLS SKFETYWKSS TAPLNSVTTP
ARQPASRQGF AAGANSANAS PALNVTGPLI AAGGTVITSS LTGEFVHLIV QVTRDLVPVV
FSRKWLPVHG FDLSIGVVTY AQFKSLSQGD TLKGDPTSTS EWHFSLSSGF YSLEDALTVL
PLTLGACIEL AWSPGSDRRP KQDLNAIVDS VLRTVYAVSR PSRTSDLQSS RHPVFFSSYC
GMLPRENHDA EASIETARGD LRQRSISGAV DFAKENNLLG VLVDARLIVS GPIVLYVVVT
DQGHPPAPSS NYSTSCPRFE YPAGFVWVTR PSDGQPTGWA RS
//
