ID L8X291_THACA Unreviewed; 885 AA.
AC L8X291;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=DNA mismatch repair proteins mutS family domain-containing protein {ECO:0000259|Pfam:PF00488};
GN ORFNames=AG1IA_02759 {ECO:0000313|EMBL:ELU43217.1};
OS Thanatephorus cucumeris (strain AG1-IA) (Rice sheath blight fungus)
OS (Rhizoctonia solani).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Cantharellales; Ceratobasidiaceae; Rhizoctonia; Rhizoctonia solani AG-1.
OX NCBI_TaxID=983506 {ECO:0000313|EMBL:ELU43217.1, ECO:0000313|Proteomes:UP000011668};
RN [1] {ECO:0000313|EMBL:ELU43217.1, ECO:0000313|Proteomes:UP000011668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AG-1 IA {ECO:0000313|Proteomes:UP000011668};
RX PubMed=23361014; DOI=10.1038/ncomms2427;
RA Zheng A., Lin R., Xu L., Qin P., Tang C., Ai P., Zhang D., Liu Y., Sun Z.,
RA Feng H., Wang Y., Chen Y., Liang X., Fu R., Li Q., Zhang J., Yu X., Xie Z.,
RA Ding L., Guan P., Tang J., Liang Y., Wang S., Deng Q., Li S., Zhu J.,
RA Wang L., Liu H., Li P.;
RT "The evolution and pathogenic mechanisms of the rice sheath blight
RT pathogen.";
RL Nat. Commun. 4:1424-1424(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004448}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELU43217.1}.
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DR EMBL; AFRT01000599; ELU43217.1; -; Genomic_DNA.
DR AlphaFoldDB; L8X291; -.
DR STRING; 983506.L8X291; -.
DR HOGENOM; CLU_325762_0_0_1; -.
DR Proteomes; UP000011668; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR GO; GO:1990542; P:mitochondrial transmembrane transport; IEA:InterPro.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR010995; DNA_repair_Rad51/TF_NusA_a-hlx.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR InterPro; IPR045315; Mtm1-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45760; FI19922P1-RELATED; 1.
DR PANTHER; PTHR45760:SF2; FI19922P1-RELATED; 1.
DR Pfam; PF00153; Mito_carr; 2.
DR Pfam; PF00488; MutS_V; 1.
DR PRINTS; PR00926; MITOCARRIER.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47794; Rad51 N-terminal domain-like; 1.
DR PROSITE; PS50920; SOLCAR; 2.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000011668};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 3..63
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|Pfam:PF00488"
FT REPEAT 293..383
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 390..489
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REGION 491..515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 500..515
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 885 AA; 94529 MW; 29173AD73E470E36 CRC64;
MGEKHPNIRN MTMQTVVDDE KRQLVMMYKF VEGVAPGSFG THVANVAGVP ASVVDRAEQV
SRDFAEVSRK KQLEKRAAVS RIPLDLQADF AQLAKLAGGL KLTDDPVQQL ESLRILKGSV
RSLLKICLRL LLLLSTNMTS TLSANAKGKQ KMLEIQPVYA KAVAAATGST MTALTSRSRI
LREILGLTRL QTQPTATVAP PTLFPRPPLQ AKAGVSSGLA SSCCRPSSLP CVRNISSLAA
AYPSHASIPG HSESLVCLWD GTWRTETIAV PASTAYMLTY DYLNHSLPVA QVAPLLTPLT
AGIAARTIVA TFVSPLELVR TRLQSTPVSP GTPHTMKSVL DGIQKMVAND GLRTLWRGLG
PTLWRDVPFS GIYWAGYESG KRIANNRGYT GVEVAFGSGA LSGMVSVVIV AALVTMPFDT
LKTRRQAALI SSAEGATNST VSLGMTGLIR QIIHTEGPTA LFAGLTPRVA KIAPACGIMI
GVGKFLSPVD PDSDEPRSGY PTDSGVSTRV GNQHRSHQTL RYTSFSHSIV ELRSELAFAG
QHYNNVHNPT YFFAKRLQPL SAILLTIQFT AFYRQSSTQA LEPPISPDHM RRDPRNMYFL
NILSALALAS VAHCASPYTR RAAVDNVVYP ELTIRTSTGL ELTARDTSPA HLNELLGRAC
CTLCTPRNTN SHDCTCCGIV VMGVGATGDT LALALTLIGR TVLSANYNHF AMPTQLNRPI
ASLQINPAHR SKLMKNGYST AADIQAVSVE ELARDLGISL EDANAISAVA QTQPQISSHI
NADSVELPAT QRTQLVIAGS QTAAELLKVP ASATALSTGN KTIDELLDGG VIRGSLLQIS
GVPGSGRSAV TRSILTSAVR EGHEILIIGG LSTSIVKILS LLVYL
//
