ID   L8X332_THACA            Unreviewed;      1060 AA.
AC   L8X332;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=NRPS-like enzyme {ECO:0000313|EMBL:ELU44620.1};
GN   ORFNames=AG1IA_01362 {ECO:0000313|EMBL:ELU44620.1};
OS   Thanatephorus cucumeris (strain AG1-IA) (Rice sheath blight fungus)
OS   (Rhizoctonia solani).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Cantharellales; Ceratobasidiaceae; Rhizoctonia; Rhizoctonia solani AG-1.
OX   NCBI_TaxID=983506 {ECO:0000313|EMBL:ELU44620.1, ECO:0000313|Proteomes:UP000011668};
RN   [1] {ECO:0000313|EMBL:ELU44620.1, ECO:0000313|Proteomes:UP000011668}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AG-1 IA {ECO:0000313|Proteomes:UP000011668};
RX   PubMed=23361014; DOI=10.1038/ncomms2427;
RA   Zheng A., Lin R., Xu L., Qin P., Tang C., Ai P., Zhang D., Liu Y., Sun Z.,
RA   Feng H., Wang Y., Chen Y., Liang X., Fu R., Li Q., Zhang J., Yu X., Xie Z.,
RA   Ding L., Guan P., Tang J., Liang Y., Wang S., Deng Q., Li S., Zhu J.,
RA   Wang L., Liu H., Li P.;
RT   "The evolution and pathogenic mechanisms of the rice sheath blight
RT   pathogen.";
RL   Nat. Commun. 4:1424-1424(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ELU44620.1}.
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DR   EMBL; AFRT01000289; ELU44620.1; -; Genomic_DNA.
DR   AlphaFoldDB; L8X332; -.
DR   STRING; 983506.L8X332; -.
DR   HOGENOM; CLU_002220_1_0_1; -.
DR   OMA; CENDRAH; -.
DR   Proteomes; UP000011668; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 2.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR013120; Far_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43439:SF2; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR   PANTHER; PTHR43439; PHENYLACETATE-COENZYME A LIGASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF07993; NAD_binding_4; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000011668}.
FT   DOMAIN          46..214
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          671..911
FT                   /note="Thioester reductase (TE)"
FT                   /evidence="ECO:0000259|Pfam:PF07993"
SQ   SEQUENCE   1060 AA;  116666 MW;  04C3EE7BFCBDDCC9 CRC64;
     MTIGLSEFDS PATDGSVSLN QLVDYHLGRN PECGFAMLVD VSESSNEQRV VKYRQLAHAT
     HRAAHTVNPG SALPQGTRVA ILTSTDTIVN IALVLGILRP FPISPRVSVA GICHLLIATE
     TVHMVSGGGS AIAHLVENVL SMMEESQQHL NIIYLPTFKE LFQPRSGDLF EPFPDPTPLS
     ENSVVAILHS SGSTGLPRPV TYTQGCILSS FVNQREQIGV LFAPGATPVV PSPDVTLRAV
     VRSQCTFLLT VPTFLEAWSH DNKAINHLKK IDGVVYAGGP LIPHVGNRLV ERGIYPSLRP
     SQPGFNKFML GVSLRAAYGA TEFGAPVEFD LVKRAPEDWI YIEFPDNIQP ELIPQNDQDG
     TYELVMLSTP IYKPFVVNYK NERGGVGYAT KDLVVPHPTK LGLWKVVGRL DDQIVLLNGE
     KTNPVPIEDQ IVKSPLIQSA IMFGREQNQT GVLIELHNQV DSLANVDYEK IINQIWPFVE
     LANSNTSTHS RIAREAIIFS ETSRPLPRTP KGNVARAAAL KLYANDITRM YAQLGQGSSL
     TSLGAPASWD DVEGVQFWLT RCVTHLLGVA SLTATLLSGV LRRALSLPPS IEPHIVAEKV
     TQQSIFNHPS ILQLATYLVQ LTNNSTSCSP SAPETSTMQT MIARYTQNMK VRHNDPDWPL
     TGSEPIESVV ITGTTGSLGS HILAQLLTNE RVKRVWAINR PRRDSGVPVI ERQRISFEDK
     ALPIVLLSHP KLTFLECNLN ENQLGLSNED YELVSTTTII HHQNAWQVDF NWNLQSFEPN
     VQGTRYLVDL ALNSTWKRAP RLVFTSSISV AGLGLPGRSL GEEYLTSSSI SLGFGYGESK
     YVAERVLEAA KMAGLETCVI RLGQLSGDRI SGSWSKTDWF PSMLASSLTI GYLPDAIGVV
     SWVPLDAAAQ SLLDSCCQVV AELPTVVHIA HPQPSAWPEL MKIVTQVIAM EFGKELPFIP
     LDEWNKMVSK ASGLYDDNDT RKRLPTVKLQ ASVDGMARVD QAIRESNNRD AETYEVFGAP
     RLDTSRCTQI SPCLRGLTGL DFDDVSRWVC YWKRVNLFVQ
//