ID L8XXI1_9GAMM Unreviewed; 136 AA.
AC L8XXI1;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=Ferric uptake regulation protein {ECO:0000256|ARBA:ARBA00020910, ECO:0000256|RuleBase:RU364037};
GN Name=fur {ECO:0000256|RuleBase:RU364037};
GN ORFNames=F387_00150 {ECO:0000313|EMBL:ELV08758.1};
OS Wohlfahrtiimonas chitiniclastica SH04.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cardiobacteriales;
OC Ignatzschineriaceae; Wohlfahrtiimonas.
OX NCBI_TaxID=1261130 {ECO:0000313|EMBL:ELV08758.1, ECO:0000313|Proteomes:UP000011617};
RN [1] {ECO:0000313|EMBL:ELV08758.1, ECO:0000313|Proteomes:UP000011617}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SH04 {ECO:0000313|EMBL:ELV08758.1,
RC ECO:0000313|Proteomes:UP000011617};
RX PubMed=23558531;
RA Cao X.M., Chen T., Xu L.Z., Yao L.S., Qi J., Zhang X.L., Yan Q.L.,
RA Deng Y.H., Guo T.Y., Wang J., Hu K.X., Xu B.L.;
RT "Complete Genome Sequence of Wohlfahrtiimonas chitiniclastica Strain SH04,
RT Isolated from Chrysomya megacephala Collected from Pudong International
RT Airport in China.";
RL Genome Announc. 1:E0011913-E0011913(2013).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|PIRSR:PIRSR602481-1};
CC Note=Binds 1 zinc ion per subunit. {ECO:0000256|PIRSR:PIRSR602481-1};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738,
CC ECO:0000256|RuleBase:RU364037}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|RuleBase:RU364037}.
CC -!- SIMILARITY: Belongs to the Fur family. {ECO:0000256|ARBA:ARBA00007957,
CC ECO:0000256|RuleBase:RU364037}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELV08758.1}.
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DR EMBL; AOBV01000002; ELV08758.1; -; Genomic_DNA.
DR RefSeq; WP_008314607.1; NZ_KB372778.1.
DR AlphaFoldDB; L8XXI1; -.
DR GeneID; 58263043; -.
DR PATRIC; fig|1261130.3.peg.355; -.
DR HOGENOM; CLU_096072_3_3_6; -.
DR OrthoDB; 8659436at2; -.
DR Proteomes; UP000011617; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd07153; Fur_like; 1.
DR Gene3D; 3.30.1490.190; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR002481; FUR.
DR InterPro; IPR043135; Fur_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR33202:SF2; FERRIC UPTAKE REGULATION PROTEIN; 1.
DR PANTHER; PTHR33202; ZINC UPTAKE REGULATION PROTEIN; 1.
DR Pfam; PF01475; FUR; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|RuleBase:RU364037};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU364037};
KW Iron {ECO:0000256|RuleBase:RU364037};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR602481-1,
KW ECO:0000256|RuleBase:RU364037};
KW Reference proteome {ECO:0000313|Proteomes:UP000011617};
KW Repressor {ECO:0000256|RuleBase:RU364037};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU364037};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU364037};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PIRSR:PIRSR602481-1}.
FT BINDING 92
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
FT BINDING 95
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
FT BINDING 132
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
FT BINDING 135
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
SQ SEQUENCE 136 AA; 15431 MW; CB08201B522CA741 CRC64;
MGSEELKNAG LKVTLPRLKI LNILVSASSE DHLSAEEIYQ RLNESGEEVG LATVYRVLTQ
FEQAGLVQRH FFDGGQSVFE LDNGDQHSHI VCVKCGYVDE FHKEEFRVKS EEIAKNFGYL
FQEAKVTIYG ICKRCQ
//
