ID L8Y0M8_TUPCH Unreviewed; 425 AA.
AC L8Y0M8;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Acyl-coenzyme A thioesterase 1 {ECO:0000313|EMBL:ELV09878.1};
GN ORFNames=TREES_T100010360 {ECO:0000313|EMBL:ELV09878.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELV09878.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- SIMILARITY: Belongs to the C/M/P thioester hydrolase family.
CC {ECO:0000256|ARBA:ARBA00006538}.
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DR EMBL; KB369403; ELV09878.1; -; Genomic_DNA.
DR AlphaFoldDB; L8Y0M8; -.
DR STRING; 246437.L8Y0M8; -.
DR eggNOG; ENOG502QQ8Z; Eukaryota.
DR InParanoid; L8Y0M8; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0016790; F:thiolester hydrolase activity; IEA:InterPro.
DR GO; GO:0006637; P:acyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 2.60.40.2240; Acyl-CoA thioester hydrolase/BAAT N-terminal domain; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR016662; Acyl-CoA_thioEstase_long-chain.
DR InterPro; IPR014940; BAAT_C.
DR InterPro; IPR006862; Thio_Ohase/aa_AcTrfase.
DR InterPro; IPR042490; Thio_Ohase/BAAT_N.
DR PANTHER; PTHR10824:SF17; ACYL-COENZYME A THIOESTERASE 6; 1.
DR PANTHER; PTHR10824; ACYL-COENZYME A THIOESTERASE-RELATED; 1.
DR Pfam; PF08840; BAAT_C; 1.
DR Pfam; PF04775; Bile_Hydr_Trans; 1.
DR PIRSF; PIRSF016521; Acyl-CoA_hydro; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000011518}.
FT DOMAIN 24..155
FT /note="Acyl-CoA thioester hydrolase/bile acid-CoA amino
FT acid N-acetyltransferase"
FT /evidence="ECO:0000259|Pfam:PF04775"
FT DOMAIN 218..425
FT /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08840"
SQ SEQUENCE 425 AA; 45767 MW; 949B5553165183FB CRC64;
MPTSSLSSPK AATLTVKPKT GLADEPLDIK VEGLGPGERV TLRATAISYR GRRFHSLAHY
QADCRGRLDL ARAPALGGDF TGVEPMGLLW SLTPAGSQDP RLSQMPRGVM RNPLKVEVTV
HRAPRQPAEP LGPALASAQV QRWFSTPELQ RARLRARGLR GVFLVPSGDG PFPGLIDMFG
DGGLNESRTS LLACRGFATL ALPLFGYEDL PPIMKDLNLD YFEEAAKFVQ SHPKVKGPNI
GVIGSGKGAE LAFSMASFLP SIAAVVSING CVSNTATTLT CGRVILPGLP LNLDKISATD
SGVYDVKEAL EDPLDPAYQE SRIPLEKASA HFLFIVGEDD RHWKSSVYAD IAMKHLTEHG
KTNFTLLSYP DAGHRIDPPY SPFFAVALDP VLGVSVLGGG QLKAHAIAQI ESWKKILEFL
HLHLG
//
