ID L8Y6T6_TUPCH Unreviewed; 387 AA.
AC L8Y6T6;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Alpha-1-antiproteinase 2 {ECO:0000313|EMBL:ELV12138.1};
GN ORFNames=TREES_T100005840 {ECO:0000313|EMBL:ELV12138.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELV12138.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- SIMILARITY: Belongs to the serpin family.
CC {ECO:0000256|RuleBase:RU000411}.
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DR EMBL; KB364711; ELV12138.1; -; Genomic_DNA.
DR AlphaFoldDB; L8Y6T6; -.
DR STRING; 246437.L8Y6T6; -.
DR MEROPS; I04.971; -.
DR eggNOG; KOG2392; Eukaryota.
DR InParanoid; L8Y6T6; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd19587; serpinA16_HongrES1-like; 1.
DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 1.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 1.
DR Gene3D; 2.10.310.10; Serpins superfamily; 1.
DR InterPro; IPR023795; Serpin_CS.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR000215; Serpin_fam.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR InterPro; IPR042185; Serpin_sf_2.
DR PANTHER; PTHR11461:SF160; SERINE (OR CYSTEINE) PEPTIDASE INHIBITOR, CLADE A (ALPHA-1 ANTIPROTEINASE, ANTITRYPSIN), MEMBER 16; 1.
DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1.
DR Pfam; PF00079; Serpin; 1.
DR SMART; SM00093; SERPIN; 1.
DR SUPFAM; SSF56574; Serpins; 1.
DR PROSITE; PS00284; SERPIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000011518}.
FT DOMAIN 16..374
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
SQ SEQUENCE 387 AA; 44042 MW; 98B748530B199BEA CRC64;
MPSASSTALN NSHFAFRLYR EMVAANPGRN VLFSPLSVSI PLTLLALKAK PAVCSQILKA
LGFSLAEVAN DQAQVHYSQL LRALLPDPWK CPTEMGSVLF VDKRRSLVRK FIDTAQNLYR
MDVFLTAFKS YATARDYMDF FIRKKTHGKI EKLTQKVNPD TVLILANYIF FKGKWKHYFD
PKLTEMRPFS VNEKLTVQVP MMHRLGYFQL QYFRHLHSYV LWLPCRCNAN TVFILPNMGK
VSETEEALLK ENFDTWTQPL TLSSKRRLYL PKFSLRANVQ LDQFTPTTGI SDIFSYSAGL
TGISLQTLPM RVSKAVHVAE LTVDEDGAEK EDITGLRFSP SHLIPILDFN RPFLLLVFAE
GSHNLLFMGK VMNPKANLSS GDKRAFP
//
