ID L8Y747_TUPCH Unreviewed; 489 AA.
AC L8Y747;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Gamma-glutamyltransferase 6 {ECO:0000313|EMBL:ELV12258.1};
GN ORFNames=TREES_T100003552 {ECO:0000313|EMBL:ELV12258.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELV12258.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- SIMILARITY: Belongs to the gamma-glutamyltransferase family.
CC {ECO:0000256|ARBA:ARBA00009381}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB364611; ELV12258.1; -; Genomic_DNA.
DR AlphaFoldDB; L8Y747; -.
DR STRING; 246437.L8Y747; -.
DR MEROPS; T03.024; -.
DR eggNOG; KOG2410; Eukaryota.
DR InParanoid; L8Y747; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.60.20.40; -; 1.
DR InterPro; IPR043137; GGT_ssub.
DR InterPro; IPR029055; Ntn_hydrolases_N.
DR PANTHER; PTHR47278; GLUTATHIONE HYDROLASE 6; 1.
DR PANTHER; PTHR47278:SF1; GLUTATHIONE HYDROLASE 6; 1.
DR Pfam; PF01019; G_glu_transpept; 1.
DR PRINTS; PR01210; GGTRANSPTASE.
DR SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Transferase {ECO:0000313|EMBL:ELV12258.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 53..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 81..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 489 AA; 49711 MW; 7823D3D80D662697 CRC64;
MEASAQPVVY QKLLLWEPSL ELEEEEDEEE ISMPLVLDLW QPQDSGAGGL LGVWVRLGAA
LLLLVLGCAL AARQFQAKAG STGSLGSATP RPSGHAHRPG VFHHGAAISP TATCSHLGRE
LLVAGGNVVD AGVGAALCLA VVHPHATGLG ATFWGLFLNS SSGNVTALTS GPARTLAPGL
GLPAALPTLH LLHTHFGRLP WPRLLEGPIM LAEEGFEVDA ALARALTAQG TKGLCPLLCH
TNGTFLGLGA RATNPKLAAV LRRATLTPTL DLAEGALLSL LARDLGLEGP SVGPTPTLEP
ALQLPMPQGT LFTTPGPSAG PDLLALLRAA LHSGVPSPDP CPLLLPTSGT PESSVLATVD
SSGSVLLLAS SLNSSFGSGH LSPSTGVLLN NLEAGSAAGA WACPLILQGG LDDTEADVLG
LVASGTPSVA RAMTHALLRH LAGPQTQVQQ GLTESHSACG QGTLLQVAVH AEHAHVASVP
DGCCPFQGF
//
