ID   L8Y8Q3_TUPCH            Unreviewed;       619 AA.
AC   L8Y8Q3;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=NACHT, LRR and PYD domains-containing protein 13 {ECO:0000313|EMBL:ELV11449.1};
GN   ORFNames=TREES_T100017427 {ECO:0000313|EMBL:ELV11449.1};
OS   Tupaia chinensis (Chinese tree shrew).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX   NCBI_TaxID=246437 {ECO:0000313|EMBL:ELV11449.1, ECO:0000313|Proteomes:UP000011518};
RN   [1] {ECO:0000313|Proteomes:UP000011518}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Zhang G., Fan Y., Yao Y., Huang Z.;
RT   "Genome of the Chinese tree shrew, a rising model animal genetically
RT   related to primates.";
RL   Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000011518}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23385571; DOI=10.1038/ncomms2416;
RA   Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA   Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA   Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA   Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA   Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT   "Genome of the Chinese tree shrew.";
RL   Nat. Commun. 4:1426-1426(2013).
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DR   EMBL; KB365142; ELV11449.1; -; Genomic_DNA.
DR   AlphaFoldDB; L8Y8Q3; -.
DR   eggNOG; ENOG502QV55; Eukaryota.
DR   InParanoid; L8Y8Q3; -.
DR   Proteomes; UP000011518; Unassembled WGS sequence.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   PANTHER; PTHR45690; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12; 1.
DR   PANTHER; PTHR45690:SF16; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 13; 1.
DR   Pfam; PF13516; LRR_6; 4.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   SMART; SM00368; LRR_RI; 8.
DR   SUPFAM; SSF52047; RNI-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000011518}.
FT   DOMAIN          52..107
FT                   /note="NOD2 winged helix"
FT                   /evidence="ECO:0000259|Pfam:PF17779"
FT   DOMAIN          109..225
FT                   /note="NACHT LRR and PYD"
FT                   /evidence="ECO:0000259|Pfam:PF17776"
SQ   SEQUENCE   619 AA;  69230 MW;  57A2EA12269B3171 CRC64;
     MCWAVCSSLK QQKARRDLQL VARTTTSLYA CFVSSLFSVA EVSWADRSWP RQWRALCALA
     AEGMWNAAFT FGKEDSRYRC LEAPFLDSLF KFSILQKVSD CEDCVTFTHA SFQEFFAAMF
     YVLEGTEGSL GHSTKYQEMK TVLSSVLVNR SIYWTPMVRL LFGLLNQDLA RKLEGTLHCK
     VSLQIMEDLL EWEEELHEPE MVSVPFDVLQ FFHCLHETQE EDFVKMMLGH IFEADLDLSG
     NMELRVSAFC LKHCGRLNKL RLSVSGPIFQ RVSDVETAEA GRIDSMHQWE ELCSAFGANR
     SVSELDLSNS KLNPASMRSL CHALRSPRCR LQKLTCKSVT PVTVLKELVL VLHGNRRLTH
     LNVSSNELGL AVSTSIFRTL RHSACNLKYL WLDSCGLNSL LCQRLFLELA ENASLHFLSL
     GDNDLSDVRI QGPKGSFEFP KCPLKELSLW FCQLGAPSCR HLSDALLRNR SLTQLNLSRN
     SLGDGGVALL CEALSRPDCS VQNLNLSDCA ITRQGCQELA NALKHNHNVQ VLDLGNNDLQ
     DEGVKPLCEA LRRPGCTLTT LGLEKCSLTP ACCQPLSSVL SSSQSLVSLN LLGNDLEVDG
     VKVLCRALRK PTCKLRKLG
//