ID L8Y9H7_TUPCH Unreviewed; 691 AA.
AC L8Y9H7;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Semaphorin-4G {ECO:0000313|EMBL:ELV11625.1};
GN ORFNames=TREES_T100016494 {ECO:0000313|EMBL:ELV11625.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELV11625.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- SIMILARITY: Belongs to the semaphorin family.
CC {ECO:0000256|ARBA:ARBA00009492}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR EMBL; KB365060; ELV11625.1; -; Genomic_DNA.
DR AlphaFoldDB; L8Y9H7; -.
DR STRING; 246437.L8Y9H7; -.
DR eggNOG; KOG3611; Eukaryota.
DR InParanoid; L8Y9H7; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR CDD; cd05872; Ig_Sema4B_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF17; SEMAPHORIN-4G; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..691
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003998365"
FT DOMAIN 35..505
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT DOMAIN 572..654
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 691 AA; 76618 MW; A53DD751BBA50D32 CRC64;
MWGRLLPLLL SFFTAIAVPG PSLRRPSREL DATPRMTIPY EELSGTRHFR GQAQNYSTLL
LEEASARLLV GARGALFSLS ARDIGDGAHK EIHWEASPEM QSKCHQKGKN NQTECFNHVR
FLQRLNATHL YACGTHAFQP LCAAIDAETF TLPTSFEEGK EKCPYDPARG FTGLIIDGGL
YTATRYEFRS IPDIRRSRHP HSLRTEEAPM HWLNDAEFVF SVLVRESKAS AGGDDDKVYY
FFTERAAEEG AGSFPQSRNS HRVARVARVC KGDLGGKKIL QKKWTSFLKA RLICHIPQYE
TLRGVCSLDA DGPARTHFYA AFTLTTQWKT LEASAICRYD LAEVQAVFAG PYMEYQDGAR
RWGRYEGGVP EPRPGSCITD SLRSRGYNSS QDLPSLVLDF VKLHPLMARP VVPTRGRPLL
LKRNVRYTHL TGTPVTTPAG PTYDLLFLGT ADGWIHKAVV LGSGMHIIEE MQVFREPQSV
ENLVVSPMQH SLYVGATSGV IQLPLSSCSR YRSCYDCILA RDPYCGWNPS THACIATTTQ
ANRSQGRRTT LIQDVERGNR GCESSRGTGP PPPLKTRSVL RGDDVLLPCD QPSNLARALW
LLNGSMGLSD GQDGYRVGVD GLLVTDTQPE HSGNYGCYAE ENGLRILLAA YSLTSNNGVP
AGPCSFAEEL SRILEKRKHT QLVEQLDESS V
//
