ID L8YA77_TUPCH Unreviewed; 581 AA.
AC L8YA77;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=G-protein-signaling modulator 1 {ECO:0000313|EMBL:ELV13152.1};
GN ORFNames=TREES_T100011217 {ECO:0000313|EMBL:ELV13152.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELV13152.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- SIMILARITY: Belongs to the GPSM family.
CC {ECO:0000256|ARBA:ARBA00006600}.
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DR EMBL; KB362898; ELV13152.1; -; Genomic_DNA.
DR AlphaFoldDB; L8YA77; -.
DR STRING; 246437.L8YA77; -.
DR InParanoid; L8YA77; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0030695; F:GTPase regulator activity; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR003109; GoLoco_motif.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45954:SF2; G-PROTEIN-SIGNALING MODULATOR 1; 1.
DR PANTHER; PTHR45954; LD33695P; 1.
DR Pfam; PF02188; GoLoco; 3.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13424; TPR_12; 2.
DR Pfam; PF13176; TPR_7; 1.
DR SMART; SM00390; GoLoco; 4.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50877; GOLOCO; 3.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 223..256
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 425..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 516..536
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 551..581
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 581 AA; 64220 MW; 5CB9B4A81F36D82A CRC64;
MEASCLELAL EGERLCKAGD FKAGVVFFEA AVQVGTEDLK TLSAVYSQLG NAYFYLKEYA
RALRFHRHDL LLARTIGDRM GEAKASGNLG NTLKVLGRFD EAIVCCQRHL DIAREQGDRV
GEARALYNIG NVYHAKGKQL SWSATQDPGH LPPDVRETLR RASEFYERNL SLVKELGDRA
AQGRACGNLG NTHHQLGAFA EATAFHKERL AIAKEFGDKA AERRAYSNLG NAHIFLGRFD
VAAEYYKKTL QLSRQLRDPA VEAQACYSLG NTYTLLRDHE RAAEHHLRHL LIARELADRV
GEGRACWSLG NAYVSMGSPA RALTFAEKHL QISQEIGDRS GELTARMNVA QLQLALGRLS
SPAAAEKPDL AGYEAQGARP KRTQRLSAEA WDLLRLPVER GIPRAPSSEE ECFFDLLSKF
QSSRREEGQA GAAEAAAPTL GERTAQPSTA SPQTEEFFDL IASSQSRRLD DQRVSVGSLP
GLRVTRNNAA HLRGDGDPQE PGDEFFNMLI KCQSSRIDDQ RCPPPDLLPR GPTMPDEDFF
SLIQRVQAKR MDEQRVDLAG SPEQEAGVLP EDQQQYQSGA S
//
