ID L8YAT8_TUPCH Unreviewed; 812 AA.
AC L8YAT8;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Vomeronasal type-2 receptor 26 {ECO:0000313|EMBL:ELV11471.1};
GN ORFNames=TREES_T100015419 {ECO:0000313|EMBL:ELV11471.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELV11471.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KB365141; ELV11471.1; -; Genomic_DNA.
DR RefSeq; XP_006166854.1; XM_006166792.1.
DR AlphaFoldDB; L8YAT8; -.
DR GeneID; 102487548; -.
DR KEGG; tup:102487548; -.
DR eggNOG; KOG1056; Eukaryota.
DR InParanoid; L8YAT8; -.
DR OrthoDB; 4188279at2759; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR004073; GPCR_3_vmron_rcpt_2.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24061:SF529; VOMERONASAL 2, RECEPTOR 53-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01535; VOMERONASL2R.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00980; G_PROTEIN_RECEP_F3_2; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:ELV11471.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 515..540
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 552..573
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 585..609
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 630..648
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 674..697
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 709..729
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 735..757
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 515..771
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 782..812
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 812 AA; 90445 MW; 8275A5FA9E556CCE CRC64;
MWGYHVAQSF VFAIEEINRD TQLLPNLTLG FSIWNSGDSV HGALHETMDF LTGQEEPVPN
YMCQPRSPRA ALVGDTRSAV SVPIARLLGL YKFPQVSHSS SLASLSDKTQ FPSFLRTLAS
DFTSSHMVAQ LVLHFRWSWV GVLAQDDDFG QQGSSLVTQE LGQAGVCIEF HLHIPSQQSL
GKTDTIIYTM ESCTATVILV FLSNSNFQLI LQGLLVHHHI LGKVWVSQDT LHIAIALSMP
GVSQVLRGSF SLLQHSTQVP GFPEFLAQLH PTHTPEDMFI ERFWEETFRC MWPHKIQGLE
KNSKAAETVQ FCSGNESLRD QNYPFQELSK VDIGYMAVYS IAHALKELLA CENEDGVCTD
PQHFLPWQLL HSLREVHFKT PDGKETMFDA NGDIVTEFDI LCGQKTEDDL FHFVRIGTID
PQSSLENRMI VRLRKENLQV PRSVCSRSCA PGSSQIPRQG FPHCCFKCSP CPDGEFADQG
DMRRCLLCPK EQYSNPARDR CLPRIETFLA FDEPLGLTLA LVALMLAALA VLVLGVFLKH
WDTPVVRANN RALSYTLLIS LTLCALCPLL FLGRPTTATC FLRQTTFAIV FTVAVSSVLA
KTLTVVLAFR VIRPGDRVRV CLRPGTSTSV VLVASLMQVM VCGVWLGTPP PFPDRDTASE
PHHIILQCQE GSETAFFCML GYLGLLAGGT FSVSFLARDL PDAFNETKFL TFSMLLFCSV
WVAFLPLYHS ARGKFTVAVE IFSILASTAG LLGSIFIPKC YITLLKPQQN VPAWLRRGGQ
AHQERQSNEL SKRPLHTTKA HKPTHTEDIR AP
//
