ID L8YCC6_TUPCH Unreviewed; 485 AA.
AC L8YCC6;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Noelin-2 {ECO:0000313|EMBL:ELV14068.1};
GN ORFNames=TREES_T100002069 {ECO:0000313|EMBL:ELV14068.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELV14068.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}. Synapse
CC {ECO:0000256|ARBA:ARBA00034103}.
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DR EMBL; KB359504; ELV14068.1; -; Genomic_DNA.
DR AlphaFoldDB; L8YCC6; -.
DR STRING; 246437.L8YCC6; -.
DR eggNOG; KOG3545; Eukaryota.
DR InParanoid; L8YCC6; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
DR InterPro; IPR022082; Noelin_dom.
DR InterPro; IPR003112; Olfac-like_dom.
DR PANTHER; PTHR23192:SF27; NOELIN-2; 1.
DR PANTHER; PTHR23192; OLFACTOMEDIN-RELATED; 1.
DR Pfam; PF12308; Noelin-1; 1.
DR Pfam; PF02191; OLF; 1.
DR SMART; SM00284; OLF; 1.
DR PROSITE; PS51132; OLF; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00446}; Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Synapse {ECO:0000256|ARBA:ARBA00023018}.
FT DOMAIN 225..477
FT /note="Olfactomedin-like"
FT /evidence="ECO:0000259|PROSITE:PS51132"
FT COILED 177..223
FT /evidence="ECO:0000256|SAM:Coils"
FT DISULFID 226..408
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00446"
SQ SEQUENCE 485 AA; 54567 MW; 6DC8124810C5E565 CRC64;
MVEGLSLLQW RLARDLAHPG GQGKGVCHFC GPLCSPSTPL GSRSLTLPSS LQTLFQSPEE
GWQLYTSAQA PDGKCICTAV IPAQSTCSRD GRSRELRQLM EKVQNVSQSM EVLELRTYRD
LQYVRGMETL MRSLDARLRA ADGSVSAKSF QELKDRMTEL SPLSSVLEQY KADTRTILRL
REEVRNLSGS LAAIQEEMGA YGYEDLQQRV MALEARLHAC AQKLGCGKLT GVSNPITIRA
MGSRFGSWMT DTMAPSADNR VWYMDGYYKG RRVLEFRTLG DFIKGQNFIQ HLLPQPWAGT
GHVVYNGSLF YNKYQSNVVV KYHFRSRSVL VQRSLPGAGY NNTFPYSWGG FSDMDFMVDE
SGLWAVYTTN QNAGNIVVSR LDPHTLEVVR SWDTGYPKRS AGEAFMICGV LYVTNSHLAG
AKVYFAYFTN TSSYEYTDVP FHNQYSHISM LDYNPRERAL YTWNNGHQVL YNVTLFHVIS
TAGDP
//
