ID L8YEN2_TUPCH Unreviewed; 613 AA.
AC L8YEN2;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Lysine-specific demethylase 4D {ECO:0000313|EMBL:ELV13544.1};
GN ORFNames=TREES_T100004631 {ECO:0000313|EMBL:ELV13544.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELV13544.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
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DR EMBL; KB361044; ELV13544.1; -; Genomic_DNA.
DR RefSeq; XP_006162657.1; XM_006162595.1.
DR AlphaFoldDB; L8YEN2; -.
DR STRING; 246437.L8YEN2; -.
DR GeneID; 102469253; -.
DR KEGG; tup:102469253; -.
DR eggNOG; KOG0958; Eukaryota.
DR InParanoid; L8YEN2; -.
DR OrthoDB; 48111at2759; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.650; Cupin; 1.
DR InterPro; IPR003347; JmjC_dom.
DR InterPro; IPR003349; JmjN.
DR PANTHER; PTHR10694; LYSINE-SPECIFIC DEMETHYLASE; 1.
DR PANTHER; PTHR10694:SF21; LYSINE-SPECIFIC DEMETHYLASE 4D; 1.
DR Pfam; PF02373; JmjC; 1.
DR Pfam; PF02375; JmjN; 1.
DR SMART; SM00558; JmjC; 1.
DR SMART; SM00545; JmjN; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51184; JMJC; 1.
DR PROSITE; PS51183; JMJN; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Methyltransferase {ECO:0000313|EMBL:ELV13544.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Transferase {ECO:0000313|EMBL:ELV13544.1}.
FT DOMAIN 16..58
FT /note="JmjN"
FT /evidence="ECO:0000259|PROSITE:PS51183"
FT DOMAIN 144..310
FT /note="JmjC"
FT /evidence="ECO:0000259|PROSITE:PS51184"
FT REGION 343..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..375
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..418
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 613 AA; 68134 MW; 9668113E4FFE6E35 CRC64;
MKSAEHSRAQ NPRCAVMTFH PTMEEFTDFN RYIAHMESQG AHRAGLAKVV PPKEWKARQT
YDDIGDILIA TPLQQVASGQ AGVFTQYHKK KKAMTVRQYH HLANSEKYRT PEHLNFDDLE
RKYWKSRLYN SPIYGADVSG SLFDQSTKQW NLGHLGTIQD LLEQECGVVI EGVNTPYLYF
GMWKTTFAWH TEDMDLYSIN YLHFGEPKTW YAVPPEHGQR LERLARELFP GSARGCEAFL
RHKVALISPT VLRENGIPFG RMTQEAGEFM VTFPYGYHAG FNHGFNCAEA INFASPRWID
YGKVASQCSC GEARVSFSMD PFVRILQPER YELWKRGQDP TVVEHREHRE HRAPRAPAGQ
ELRASRKDRG PRKATERGRP LHKRRVGRPR HAVTSSDGTG SQAFMQSTPS LDARGATTQD
KVTATVSFLK PPQATSLMAE VSIPDLHSSN GSRSPGGRRP LVVRSQEMTH QALAKRLRVG
DTVHTACGPR AQSLPVDGTL MDKPAPASPG LQHPANGCCC APDLQPLGPP LDPNAPMHPG
SCLGSLDSFV QCFSEVVLHT DPNSVVPQST FPWDAAGACA APENQAEVVA LDHSYACSIL
TSPALARIFC IPD
//
