ID L9JBB5_TUPCH Unreviewed; 314 AA.
AC L9JBB5;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Taste receptor type 2 {ECO:0000256|RuleBase:RU004424};
GN ORFNames=TREES_T100001088 {ECO:0000313|EMBL:ELW47544.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW47544.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU004424}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU004424}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor T2R family.
CC {ECO:0000256|ARBA:ARBA00007376, ECO:0000256|RuleBase:RU004423}.
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DR EMBL; KB321105; ELW47544.1; -; Genomic_DNA.
DR RefSeq; XP_006159649.1; XM_006159587.1.
DR AlphaFoldDB; L9JBB5; -.
DR STRING; 246437.L9JBB5; -.
DR GeneID; 102496632; -.
DR KEGG; tup:102496632; -.
DR CTD; 338398; -.
DR eggNOG; ENOG502S2SI; Eukaryota.
DR InParanoid; L9JBB5; -.
DR OrthoDB; 4642354at2759; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0033038; F:bitter taste receptor activity; IEA:InterPro.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15018; 7tm_TAS2R41-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR007960; TAS2R.
DR PANTHER; PTHR11394; TASTE RECEPTOR TYPE 2; 1.
DR PANTHER; PTHR11394:SF32; TASTE RECEPTOR TYPE 2 MEMBER 60; 1.
DR Pfam; PF05296; TAS2R; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
PE 3: Inferred from homology;
KW G-protein coupled receptor {ECO:0000256|RuleBase:RU004424};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU004424};
KW Receptor {ECO:0000256|RuleBase:RU004424, ECO:0000313|EMBL:ELW47544.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606,
KW ECO:0000256|RuleBase:RU004424};
KW Taste {ECO:0000256|ARBA:ARBA00022480, ECO:0000256|RuleBase:RU004424};
KW Transducer {ECO:0000256|RuleBase:RU004424};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU004424};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 314 AA; 36109 MW; 9C5EA2ECCDDD615B CRC64;
MNGDDMVPGP PGTDRKSVIS AVILFFVCLL AVVSNGFITS ALCMEWLLRR TLLPCDKLLV
SLGASRFCLQ WVVMGKIFYI LLNPMAFPYN PMHQFFAFQW DFLNSLTLWF STWLSVFYCV
KIATFTHPAF LWLKCRLSKW VPWMLLSSLG VSNLNTILFF IGNYEVYQNY LRRDLQPWNA
TETSVRSFYE RFYFFSLKMI SFTVPTVVFI ICMALLTISL GKHLKKAFVT ISGFRDPSAQ
AHIKALLALI SFAILFISSF LSLVIHAAGM FPVWEFRYWT WQVVSHLCMA VHPISLIFSN
PKLKAVLERG CSSR
//
