ID L9JEK5_TUPCH Unreviewed; 872 AA.
AC L9JEK5;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Bromodomain-containing protein 1 {ECO:0000313|EMBL:ELW49025.1};
GN ORFNames=TREES_T100000898 {ECO:0000313|EMBL:ELW49025.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW49025.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
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DR EMBL; KB321007; ELW49025.1; -; Genomic_DNA.
DR AlphaFoldDB; L9JEK5; -.
DR STRING; 246437.L9JEK5; -.
DR InParanoid; L9JEK5; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR CDD; cd05512; Bromo_brd1_like; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 2.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR000313; PWWP_dom.
DR PANTHER; PTHR22881; BROMODOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22881:SF42; LD22651P; 1.
DR Pfam; PF00439; Bromodomain; 2.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 2.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF47370; Bromodomain; 2.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 2.
DR PROSITE; PS50014; BROMODOMAIN_2; 2.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518}.
FT DOMAIN 270..323
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 407..477
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 581..605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 619..704
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 194..244
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 620..646
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 679..695
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 872 AA; 97795 MW; 91D901BDAAD902FF CRC64;
MLSCRRGQVR STLCCVSSRV RGSLAGGGLV LPAGQHLVCA AAWLVQPGPR RASVSWSGTA
VTLVAVDEAS SEPWLALGAS QEARRPCRFG DTAALLLAVL PLELLQPCMR LAPLPRETGE
QPFPDSGPCG PERLGLNRIA NQVAVQRKKQ FVERAHSYWL LKRLSRNGAP LLRRLQSSLQ
SQRSSQQREN DEEVKAAKEK LQYWQRLRHD LERARLLIEL LRKREKLKRE QVKVEQMAME
LRLTPLAVLL RSVLDQLQEK DPARIFAQPV PDYLDHIKHP MDFATMRKRL EAQGYKNLHE
FEEDFDLIVD NCMRYNAKDT VFYRAAVRLR DQGGVVLRQA RRQVDSIGLE EASGMHLPER
PAAAPRRPFS WEDGKNRTVF VKVEQMAMEL RLTPLAVLLR SVLDQLQEKD PARIFAQPVS
LKEVPDYLDH IKHPMDFATM RKRLEAQGYK NLHEFEEDFD LIVDNCMRYN AKDTVFYRAA
VRLRDQGGVV LRQARRQVDS IGLEEASGMH LPERPAAAPR RPFSWEDVDR LLDPANRAHL
GLEEQLRELL EKLDLTYAMK SSGSRSKRAK LLRKEIALLR NKLSQQHSQP PAAGSGTGGL
EEDSAPLGLE APEEVLPRLE TLLQPRKRSR STCGDSEAEE ESPGKRLDTG LANGFGGARS
EQDLGSGPGR RAPPRRRCAS ESSISSSSSP LCDPSFSTPR CGRGKPALVR RHTLEDRSEL
ISCIENGNYA KAARIAAEVG QNSMWISPGA AASVLEPLKV IIDPKMPRVA GHHNGVTIPA
PPLDVLKIGE HMQTKSDEKL FLVLFFDNKR SWQWLPKSKM VPLGVDEAID KLKMMEGRSS
GIRKAVRVAF DRAMNHLSRV HGEPASDLSD ID
//
