ID   L9JG44_TUPCH            Unreviewed;       438 AA.
AC   L9JG44;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=Ectonucleoside triphosphate diphosphohydrolase 7 {ECO:0000313|EMBL:ELW49338.1};
GN   ORFNames=TREES_T100012308 {ECO:0000313|EMBL:ELW49338.1};
OS   Tupaia chinensis (Chinese tree shrew).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX   NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW49338.1, ECO:0000313|Proteomes:UP000011518};
RN   [1] {ECO:0000313|Proteomes:UP000011518}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Zhang G., Fan Y., Yao Y., Huang Z.;
RT   "Genome of the Chinese tree shrew, a rising model animal genetically
RT   related to primates.";
RL   Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000011518}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23385571; DOI=10.1038/ncomms2416;
RA   Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA   Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA   Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA   Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA   Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT   "Genome of the Chinese tree shrew.";
RL   Nat. Commun. 4:1426-1426(2013).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SIMILARITY: Belongs to the GDA1/CD39 NTPase family.
CC       {ECO:0000256|ARBA:ARBA00009283}.
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DR   EMBL; KB320999; ELW49338.1; -; Genomic_DNA.
DR   AlphaFoldDB; L9JG44; -.
DR   eggNOG; KOG1386; Eukaryota.
DR   InParanoid; L9JG44; -.
DR   Proteomes; UP000011518; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.420.40; -; 2.
DR   Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR   InterPro; IPR000407; GDA1_CD39_NTPase.
DR   PANTHER; PTHR11782; ADENOSINE/GUANOSINE DIPHOSPHATASE; 1.
DR   PANTHER; PTHR11782:SF37; ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 7; 1.
DR   Pfam; PF01150; GDA1_CD39; 2.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:ELW49338.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        350..368
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   438 AA;  50141 MW;  5905E0ACBC8A8340 CRC64;
     MATRRLLNER QTTEQDDGEV SGGISAMADT PEHASDYLRP LLSFAAAHVP VKKHKETPLY
     ILCTAGMRLL PESRAQTDQE EAAKVLLAEF NLGCDVQHTE HVYRVYVTTF LGFGGNFARQ
     RYEDLVLNET LNKNRLLGQK TGLSPDNPFL DPCLPVGLTD VVERNGQVLH VRGKGQWATC
     GAMLSPLLAR SNTSQASLNG IYQSPIDFNN SEFYGFSEFF YCTEDVLRIG GRYHGPTFAK
     AAQDYCGMSW SVLSQRFKNG LFSSHADEHR LKYQCFKSAW MYQVLHEGFH FPYDYPNLRT
     AQLVYDREVQ WTLGAILYKT RFLPLRDLRQ EGVRQAHSSW LRLSFVYNHY LFFACILVVL
     LAIILYLLRL RRIHHRQTRA SAPLDLLWIE EVVPMIGVQT ILFSERSCNL VCEEQNDQRL
     VLTKGTKERP VEACSYFT
//