ID   L9JQL9_TUPCH            Unreviewed;      1317 AA.
AC   L9JQL9;
DT   03-APR-2013, integrated into UniProtKB/TrEMBL.
DT   03-APR-2013, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Anaphase-promoting complex subunit 1 {ECO:0000313|EMBL:ELW51457.1};
GN   ORFNames=TREES_T100021659 {ECO:0000313|EMBL:ELW51457.1};
OS   Tupaia chinensis (Chinese tree shrew).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX   NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW51457.1, ECO:0000313|Proteomes:UP000011518};
RN   [1] {ECO:0000313|Proteomes:UP000011518}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Zhang G., Fan Y., Yao Y., Huang Z.;
RT   "Genome of the Chinese tree shrew, a rising model animal genetically
RT   related to primates.";
RL   Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000011518}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23385571; DOI=10.1038/ncomms2416;
RA   Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA   Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA   Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA   Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA   Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT   "Genome of the Chinese tree shrew.";
RL   Nat. Commun. 4:1426-1426(2013).
CC   -!- SIMILARITY: Belongs to the APC1 family.
CC       {ECO:0000256|ARBA:ARBA00010547}.
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DR   EMBL; KB320971; ELW51457.1; -; Genomic_DNA.
DR   STRING; 246437.L9JQL9; -.
DR   eggNOG; KOG1858; Eukaryota.
DR   InParanoid; L9JQL9; -.
DR   Proteomes; UP000011518; Unassembled WGS sequence.
DR   GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR024990; Apc1.
DR   InterPro; IPR048971; Apc1_3rd.
DR   InterPro; IPR041221; APC1_C.
DR   InterPro; IPR046794; Apc1_MidN.
DR   InterPro; IPR049255; Apc1_N.
DR   InterPro; IPR011989; ARM-like.
DR   PANTHER; PTHR12827:SF3; ANAPHASE-PROMOTING COMPLEX SUBUNIT 1; 1.
DR   PANTHER; PTHR12827; MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER; 1.
DR   Pfam; PF12859; ANAPC1; 1.
DR   Pfam; PF21282; APC1_3rd; 1.
DR   Pfam; PF18122; APC1_C; 1.
DR   Pfam; PF20518; Apc1_MidN; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          346..421
FT                   /note="Anaphase-promoting complex subunit 1 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12859"
FT   DOMAIN          423..463
FT                   /note="Anaphase-promoting complex subunit 1 middle"
FT                   /evidence="ECO:0000259|Pfam:PF20518"
FT   DOMAIN          1055..1103
FT                   /note="Anaphase-promoting complex subunit 1 beta-sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF21282"
FT   DOMAIN          1105..1264
FT                   /note="Anaphase-promoting complex subunit 1 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18122"
SQ   SEQUENCE   1317 AA;  145748 MW;  C82AE8F342F190BD CRC64;
     MIAAGDLQEF VPFGRDHCKH HPNALNLQLR QLQPASELWS SDGAAGLVGS LQEVTIHEKQ
     KESWQLRKGI SEIGEEVDYD EELYVAGNMV IWSKGSKSQA LAVYKAFTVD SPVQQALWCD
     FIISQDKSEK VYSLFGSSRV QYVVDHAMKI VFLNTDPSIV MTYDAVQNLH SVWALRRVKA
     EEENAVLKFS EQGGTPQNAA TSSSLTAHLR SLSKGDSPVA SPFQNYSSIH SQSRSASSPS
     LHSRSPSISN MAALSCVKFQ ESNDKTQLIF GSVTNIHAKD AAPVEKIDTM LVLEGSGNLV
     LYTGVVRVVL LSPVPELRDS SKLHDSLYNE DCTFQQLGTY IHSIRDPVHN RVTLELSNGS
     MVRITIPEIA TSELVQTCLQ AIKLILPKEI AVQMLVKWYN VHSAPGGPSY HSEWNLFVTC
     LMNMMGYNTD RLAWTRNFDF EGSLSPVIAP KKARPSETGS DDSIALYILG DENSVSDETS
     QYLSRITSGT ETEEEDDGMN DMNQEVMSLI WSEDLRVQDV RRLLQSAHPV RVNVVQYPEL
     SDHEFIEEKE NRLLQLCQRT MALPVGRGMF TLFSYHPVPT EPLPIPKLNL TGRAPPRNTT
     VDLNSGNIDV PPNMTSWASF HNGVAAGLKI APASQIDSAW IVYNKPKHAE LANEYAGFLM
     ALGLNGHLTK LATLNIHDYL TKGHEMTSIG LLLGVSAAKL GTMDMSITRL LSIHIPALLP
     PTSTELDVPH NVQVAAVVGI GLVYQGTAHR HTAEVLLAEI GRPPGPEMEY CTDRESYSLA
     AGLALGMVCL GEGDTINVDV TCPGATLALA MIYLKTNNRS IADWLRAPDT MYLLDFVKPE
     FLLLRTLARC LILWDDILPN SKWVDSNVPQ IIRENSISLS EIELPCSEDL NLETLSQAHV
     YIIAGACLSL GFRFAGSENL SAFNCLHKFA KDFMTYLSAP NASVTGPYNL ETCLSVVLLS
     LAMVMAGSGN LKVLQLCRFL HMKTGGEMNY GFHLAHHMAL GLLFLGGGRY SLSTSNSSIA
     ALLCALYPHF PAHSTDNRYH LQALRHLYVL AAEPRLLVPV DVDTNTPCYA LLEVTYKGTQ
     WYEQTKEELM APTLLPELHL LKQPETISAF TSDPALLSFA EYFCKPTVNM GQKQEILDLF
     SSVLYECVTQ ETPEMLPAYI AMDQAIRRLG RREMSETSEL WQIKLVLEFF SSRSHQERLQ
     NHPKRGLFMN SEFLPVVKCT IDNTLDQWLQ AGGDTCVHAY LNGQPFEESQ LSMLACFLVY
     HSVPAPRHLP PLGLEAKNAS ASFAEIGSFA SWKSTANGDV IMSDDKPTLN HNLCTKM
//