ID L9JU53_TUPCH Unreviewed; 586 AA.
AC L9JU53;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 13-SEP-2023, entry version 38.
DE SubName: Full=Protocadherin alpha-3 {ECO:0000313|EMBL:ELW54070.1};
GN ORFNames=TREES_T100019663 {ECO:0000313|EMBL:ELW54070.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW54070.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
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DR EMBL; KB320943; ELW54070.1; -; Genomic_DNA.
DR AlphaFoldDB; L9JU53; -.
DR InParanoid; L9JU53; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 4.
DR Gene3D; 2.60.40.60; Cadherins; 4.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF327; PROTOCADHERIN ALPHA-3; 1.
DR Pfam; PF00028; Cadherin; 3.
DR Pfam; PF08266; Cadherin_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 4.
DR SUPFAM; SSF49313; Cadherin-like; 4.
DR PROSITE; PS00232; CADHERIN_1; 2.
DR PROSITE; PS50268; CADHERIN_2; 4.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..586
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003999230"
FT TRANSMEM 468..488
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..133
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 134..242
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 243..350
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 351..461
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
SQ SEQUENCE 586 AA; 63978 MW; 7A2E053BCA07AB78 CRC64;
MVFSWREDPG AQRLLLSLLF LAIWEEGSGQ LHYSVLEEAK HGTFVGRIAQ DLGLELEDLV
PRLFRVASKG RADLLEVNLQ NGILFVNSRI DREELCGRSA ECSVHLEVIV ERPLQVFHVE
VEVKDINDNP PVFPMAVKNL FIYESRQPGS RFSLEGASDA DIGANSLLTY SLDSSEYFTL
DVKRNDEEIK SLGLVLKKLL NREDIPNHHL LIKAIDGGKP ELTGTTQLNV TVLDVNDNAP
TFEKTVYKVR LFENAPNGTL VVIVNASDLD EGINKDIEYS FNTDISADIL SKFHLDPVNG
YISVKGKIDF EETKSYEIQV EAIDKGTPPM ADHCTVLVEI VDTNDNVPEL YIKSLSLPVL
ENSPVGTVIA LISVSDQDSG ANGQVTCSLT PYGPFKLVST FKNYYSLVLD SALDRESISD
YTVVVTARDG GSPSLWATAS VSVEAPKASS RAMVGAAGPE STLVDVNVYL IIAICAVSSL
LVLTLLLYTA LRCSAPPPEG ACGPGKPTLV CSSAVGSWSY SQQRRSQRVC SGEGPPKTDL
MAFSPSLPPC PVSGDSREQL AVDVDLSDKV SNFSLFFLKY SYFYSL
//
