ID L9JX56_TUPCH Unreviewed; 526 AA.
AC L9JX56;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Keratin, type I cytoskeletal 16 {ECO:0000313|EMBL:ELW54948.1};
GN ORFNames=TREES_T100004405 {ECO:0000313|EMBL:ELW54948.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW54948.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR EMBL; KB320933; ELW54948.1; -; Genomic_DNA.
DR AlphaFoldDB; L9JX56; -.
DR SMR; L9JX56; -.
DR STRING; 246437.L9JX56; -.
DR eggNOG; ENOG502R8V7; Eukaryota.
DR InParanoid; L9JX56; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF105; KERATIN, TYPE I CYTOSKELETAL 16; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518}.
FT DOMAIN 165..476
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 475..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 169..203
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 261..354
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 420..461
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 526 AA; 57469 MW; ECAB6706A95636DC CRC64;
MLLCWAEVPP CQGSGWVAQE AIVKSPQCAQ RAQPVEAVAA VLEEVPGDGV LNVGSLSVAG
HVCLWLDGGT QLWAPRRDSR FPHTYPAHCT CFSPAVSQAE AAGGACGLGG GYGGGFSSSS
SFGGALGSGF GGGYGGGFGG GFGGGFGAGF GAGFGGGDGL LSGNEKITMQ NLNDRLASYL
DKVRALEEAN ADLEVKIRDW YQRQRPTEVK DYSPYFRTIE DLKSKIITAT IENAQPILQI
DNARLAADDF RTKYEHELAM RQSVEADING LRRVLDELTL ARTDLQMQIE SLNEELAYLK
KNHEEEMLAM RGQTGGDVSV EMDAAPGVDL SRILNEMRDQ YEQMAEKNRR DAEAWFLSKT
EELNKEVASN SELIQSGRSE VSELRRVFQG LEIELQSQLS MKASLENSLE ETKGRYCMQL
AQIQGMISSV EEQLAQLRCE MEQQSQEYKI LLDVKTRLEQ EIATYRRLLE GEDAHLSSSQ
HTSGQSYSSH DVSYSSSSSS STGRQTRPIL KEQSSFSQSQ SQSSKH
//
