ID L9K1W1_TUPCH Unreviewed; 537 AA.
AC L9K1W1;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE SubName: Full=Procollagen C-endopeptidase enhancer 1 {ECO:0000313|EMBL:ELW56479.1};
GN ORFNames=TREES_T100020753 {ECO:0000313|EMBL:ELW56479.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW56479.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
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DR EMBL; KB320921; ELW56479.1; -; Genomic_DNA.
DR AlphaFoldDB; L9K1W1; -.
DR STRING; 246437.L9K1W1; -.
DR eggNOG; ENOG502QTZ9; Eukaryota.
DR InParanoid; L9K1W1; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR CDD; cd00041; CUB; 2.
DR CDD; cd03576; NTR_PCOLCE; 1.
DR Gene3D; 2.40.50.120; -; 1.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 2.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR001134; Netrin_domain.
DR InterPro; IPR018933; Netrin_module_non-TIMP.
DR InterPro; IPR035814; NTR_PCOLCE.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR008993; TIMP-like_OB-fold.
DR PANTHER; PTHR24251; OVOCHYMASE-RELATED; 1.
DR PANTHER; PTHR24251:SF24; PROCOLLAGEN C-ENDOPEPTIDASE ENHANCER 1; 1.
DR Pfam; PF00431; CUB; 2.
DR Pfam; PF01759; NTR; 1.
DR SMART; SM00643; C345C; 1.
DR SMART; SM00042; CUB; 2.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 2.
DR SUPFAM; SSF50242; TIMP-like; 1.
DR PROSITE; PS01180; CUB; 2.
DR PROSITE; PS50189; NTR; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00059}; Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..537
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003999334"
FT DOMAIN 37..149
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 184..298
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 362..481
FT /note="NTR"
FT /evidence="ECO:0000259|PROSITE:PS50189"
FT REGION 296..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 497..520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..337
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 184..211
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
SQ SEQUENCE 537 AA; 58112 MW; 3E9C7404C8AEC7E6 CRC64;
MLPAATASLL GLFLTAWALL PFTQGQTPNY TRPVFLCGGD VTGESGYVAS EGFPNHYPPN
KECTWTITVL EGQTVSLSFR VFDLEQHPAC RYDALEVFAG SGTSGQRLGR FCGTFRPAPL
VAPGNQVTLK MTADEGTGGR GFLLWYSGRA TSGTGPPPGA RRKWVTDPRV EWAAWGYWDE
HQFCGGRLEK AQGTLTTPNW PESDYPPGIS CSWHIIAPQD QVIKLTFGKF DLEPDSYCRY
DSVSVFNGAV SDDAKRLGKF CGDTAPGPIS SEGNELLVQF VSDLSVTADG FSASYKTLPR
GTAKEGPSSG EDTLPGPPLL VPSSKPKVKP PTKTQLPPME KPEASPETEA TPVGPDTSSV
QCPKQCRRTG SLQSNFCANN LVVTATVKSM VRGPGEGLTV TVTLIGAYKT GGLDLPSPPT
GTPLKFYVPC KQCPPMKKGT SYLLMGQVEE NRGPILPPES FVVLFRPNQD QILTSLSKRK
CPSQPVSIVA RAAVRRRKPD GAGPELRMDR RHRYSALGER EVCDGRARER RLRPADP
//
