ID L9KLW8_TUPCH Unreviewed; 573 AA.
AC L9KLW8;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Olfactory receptor 2A5 {ECO:0000313|EMBL:ELW62122.1};
GN ORFNames=TREES_T100004199 {ECO:0000313|EMBL:ELW62122.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW62122.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KB320836; ELW62122.1; -; Genomic_DNA.
DR AlphaFoldDB; L9KLW8; -.
DR STRING; 246437.L9KLW8; -.
DR eggNOG; ENOG502QVH7; Eukaryota.
DR InParanoid; L9KLW8; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 2.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR PANTHER; PTHR26453; OLFACTORY RECEPTOR; 1.
DR PANTHER; PTHR26453:SF227; OLFACTORY RECEPTOR 1340; 1.
DR Pfam; PF13853; 7tm_4; 2.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 2.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Olfaction {ECO:0000256|ARBA:ARBA00022725};
KW Receptor {ECO:0000313|EMBL:ELW62122.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011518};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022725};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 321..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 401..423
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 461..486
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 498..521
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 536..553
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..258
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT DOMAIN 302..551
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 573 AA; 64223 MW; AE56BC393F705C61 CRC64;
MIYLLIILGN SLITVLICLD SHLHTPMYFF IGTLSMLDLG YTTTTVPQML AHLASQKKTI
SFTSCVAQMY IFLVLGITES WLFAIMSIDR YVAICHPLRY KVIMSPRLCG VMVIFCGLWG
VTSAFVYTIF AMRLPYCGPN KINHFFCEVP AVLKLACADT SVNDRVDFIL GFSVILIPLS
LILIIYINIF IAILKIRSAQ GQMKAFSTCA SHITVVTMFC VPAMVMYMKP GSKSSPEDDK
KLALFYNVIS AFLNPIIYSL RNKDVKRAFL KVIGVGRAPE NPRTNWILFF IFLFLYLFTV
LGNGLIVTLI RVDARLHTPM YFFLSILSLL DLSYATTTVP QMLVHLASKN KTISYVGCVV
QMYVFLTLGI TETWIFAAMA YDRYVAICHP LHYGVQMSQG LCVLLAVSSA LCGLACALVY
TVFAMKLPYC GPNEINHFFC EIPAVLKLAC ADTSLNDQVD FILGFILLLI PLSLILASYV
RIFVAILKIR STQGRIKAFS TCASHITVVT MFCIPCMIMY MRPGSEASPE DDKKLALFYN
VISAFLNPII YSLRNKDVKR AFLKFIGMSE DTE
//
