ID L9KNC4_TUPCH Unreviewed; 121 AA.
AC L9KNC4;
DT 03-APR-2013, integrated into UniProtKB/TrEMBL.
DT 03-APR-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Interleukin-18 {ECO:0000256|ARBA:ARBA00016740};
DE AltName: Full=Interferon gamma-inducing factor {ECO:0000256|ARBA:ARBA00032439};
DE AltName: Full=Interleukin-1 gamma {ECO:0000256|ARBA:ARBA00032727};
GN ORFNames=TREES_T100013195 {ECO:0000313|EMBL:ELW64253.1};
OS Tupaia chinensis (Chinese tree shrew).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia.
OX NCBI_TaxID=246437 {ECO:0000313|EMBL:ELW64253.1, ECO:0000313|Proteomes:UP000011518};
RN [1] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Zhang G., Fan Y., Yao Y., Huang Z.;
RT "Genome of the Chinese tree shrew, a rising model animal genetically
RT related to primates.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23385571; DOI=10.1038/ncomms2416;
RA Fan Y., Huang Z.Y., Cao C.C., Chen C.S., Chen Y.X., Fan D.D., He J.,
RA Hou H.L., Hu L., Hu X.T., Jiang X.T., Lai R., Lang Y.S., Liang B.,
RA Liao S.G., Mu D., Ma Y.Y., Niu Y.Y., Sun X.Q., Xia J.Q., Xiao J.,
RA Xiong Z.Q., Xu L., Yang L., Zhang Y., Zhao W., Zhao X.D., Zheng Y.T.,
RA Zhou J.M., Zhu Y.B., Zhang G.J., Wang J., Yao Y.G.;
RT "Genome of the Chinese tree shrew.";
RL Nat. Commun. 4:1426-1426(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the IL-1 family.
CC {ECO:0000256|ARBA:ARBA00010448}.
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DR EMBL; KB320750; ELW64253.1; -; Genomic_DNA.
DR AlphaFoldDB; L9KNC4; -.
DR STRING; 246437.L9KNC4; -.
DR eggNOG; ENOG502SDJZ; Eukaryota.
DR InParanoid; L9KNC4; -.
DR Proteomes; UP000011518; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0005125; F:cytokine activity; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR GO; GO:0010557; P:positive regulation of macromolecule biosynthetic process; IEA:UniProt.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR015529; IL-18.
DR InterPro; IPR000975; IL-1_fam.
DR InterPro; IPR008996; IL1/FGF.
DR PANTHER; PTHR10078; INTERLEUKIN-1 FAMILY MEMBER; 1.
DR PANTHER; PTHR10078:SF35; INTERLEUKIN-18; 1.
DR Pfam; PF00340; IL1; 1.
DR PRINTS; PR01933; INTRLEUKIN18.
DR SUPFAM; SSF50353; Cytokine; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000011518}.
SQ SEQUENCE 121 AA; 13731 MW; 0BAB5FD6611F49EF CRC64;
MPDTDSNKSQ VKFKIFMYRD SLIRGLAVAI SVEYNEISTL SCENKTLSFK NISPPDNISD
TKSDIIFFQS KVPGHNKMQF ESSSYEGHFL ACVKENDLFK LTLKKKGDCK DKSVMFTVEA
N
//
